Vaccine Development

Therapeutic vaccination to block receptor-ligand interactions possible

Published in Vaccine Weekly, August 13th, 2003

The development of a therapeutic vaccine to block receptor-ligand interactions is possible, say researchers in Switzerland.

According to published research from Switzerland, "Many chronic diseases are caused by non-physiological interactions of certain ligands with their receptors. Conventional treatment of these diseases with synthetic drugs or monoclonal antibodies (mAbs) is efficient, but problematic due to the non-compliance of patients and the risk of adverse side effects.

"Novel therapeutic approaches are focusing on strategies of active immunization aimed at the induction of a humoral immune response directed against the deleterious...

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Source: Vaccine Weekly (2003-08-13)

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