Cancer Vaccine
Protein vaccines induce protective and therapeutic antitumor responses
Published in Vaccine Weekly, September 17th, 2003
According to recent research from Denmark, "Overexpression of the growth factor receptor HER-2 (c-erbB-2, neu) has transforming potential and occurs in approximately 20-30% of breast and ovarian cancers. HER-2 is a self antigen, but antibodies and T cells specific for HER-2 have been isolated from cancer patients, suggesting HER-2 may be a good target for active immunotherapy."
"We constructed rat HER-2 DNA and protein vaccines containing potent Th cell epitopes derived from tetanus toxin and...
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Source: Vaccine Weekly (2003-09-17)
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