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Dengue Fever

Dengue fever vaccine best delivered at one year of age

Published in Vaccine Weekly, October 22nd, 2003

The dengue fever vaccine is best delivered at one year of age.

"Antibodies of all four dengue virus serotypes were detected by hemagglutination inhibition (HI) in 97% of 2,000 infants' cord sera at the time of delivery. In comparison with 250 mother-infant's paired sera, we found that 53% of the infants' serum HI titers were higher than those of the mother's," investigators in Thailand and the U.S. report.

" The mother/infant IgG subclasses 1, 2, 3, and 4 titers were 53.1/87.0, 8.4/11.7, 0.14/0.11, and 1.1/1.0 mg/dL, respectively," stated Veerachai Watanaveeradej and collaborators at Phramongkutklao Hospital and the Armed Forces Research Institute of...

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