Toxoplasmosis

Long-term protective immune response elicited by Toxoplasma gondii vaccine

Published in Vaccine Weekly, October 22nd, 2003

A long-term protective immune response was elicited by vaccination with an expression genomic library of Toxoplasma gondii.

According to a study from Brazil, "Immunization of BALB/c mice with an expression genomic library of Toxoplasma gondii induces a Th1-type immune response, with recognition of several T. gondii proteins (21 to 117 kDa) and long-term protective immunity against a lethal challenge."

"These results support further investigations to achieve a multicomponent anti-T. gondii DNA vaccine," wrote Alberto Fachado at the Oswaldo Cruz Institute in Brazil and collaborators in Argentina, Brazil, and Cuba.

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Source: Vaccine Weekly (2003-10-22)

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