Vaccine Development
Multigene DNA prime-boost vaccines for SHIV89.6P developed
Published in Vaccine Weekly, October 22nd, 2003
"We assessed four prime-boost vaccine regimens with a Gene Gun component for SHJV89.6P in Macaca nemestrina. A dosing, experiment using beta-galactosidase plasmid showed that 30 or 45 shots per dose elicited higher titer antibody than smaller doses," scientists in the United States report.
"For SHIV89.6P, we administered a six-plasmid vaccine capable of producing non-infectious virions in vivo in combination with either vaccinia recombinants or inactivated virus," stated Nicole A. Doria-Rose and collaborators at the Seattle Biomedical Research Institute and...
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Source: Vaccine Weekly (2003-10-22)
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