Autoimmune Disease
Protein microarrays guide DNA vaccine treatment of autoimmune disease
Published in Vaccine Weekly, October 29th, 2003
"The diversity of autoimmune responses poses a formidable challenge to the development of antigen-specific tolerizing therapy. We developed 'myelin proteome' microarrays to profile the evolution of autoantibody responses in experimental autoimmune encephalomyelitis (EAE), a model for multiple sclerosis (MS)," an international team of scientists reports.
"Increased diversity of autoantibody responses in acute EAE predicted a more severe clinical course," stated William H. Robinson at Stanford University and collaborators throughout the world. "Chronic EAE was...
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Source: Vaccine Weekly (2003-10-29)
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