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Childhood Immunization

New vaccines may address need to protect newborns in the developing world

Published in Vaccine Weekly, October 29th, 2003

In a new research study, two prototype oral vaccines have both been shown capable of inducing protection against a dangerous virus in newborn mice.

If the new vaccines are able to do the same for human newborns, they might be able to address an important window of immunological vulnerability in the lives of infant children. Particularly in the developing world, where the threat of infectious diseases is generally greater than in the developed world, many lives might be saved with vaccines of this type.

The vaccines are based on human and chimpanzee adenoviruses that have been altered in the laboratory so that they are unable to replicate. In the...

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