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HIV/AIDS Vaccine

Adenoviral vector HIV vaccine stimulates enhanced mucosal IgA response

Published in Vaccine Weekly, October 29th, 2003

An intranasal adenoviral vector human immunodeficiency virus vaccine stimulated an enhanced mucosal immunoglobulin A response.

According to recent research published in the Journal of Virology, "Replication-defective adenovirus (ADV) vectors represent a promising potential platform for the development of a vaccine for AIDS. Although this vector is typically administered intramuscularly, it would be desirable to induce mucosal immunity by delivery through alternative routes. In this study, the immune response and biodistribution of ADV vectors delivered by different routes were evaluated."

"ADV vectors expressing human immunodeficiency virus...

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