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Toxoplasmosis

Dendritic cells provide protection against Toxoplasma gondii

Published in Vaccine Weekly, October 29th, 2003

Murine mesenteric lymph node dendritic cells provided a protective mucosal Th2 immune response against Toxoplasma gondii.

"Toxoplasma gondii, an obligate intracellular parasite pathogen which initially invades the intestinal epithelium before disseminating throughout the body, may cause severe sequelae in fetuses and life-threatening neuropathy in immunocompromised patients. Immune protection is usually thought to be performed through a systemic Th1 response; considering the route of parasite entry it is important to study and characterize the local mucosal immune response to T. gondii," scientists in France report.

"Despite...

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