Streptococcal Vaccine
Group A streptococcal C5a peptidase is effective vaccine antigen
Published in Vaccine Weekly, November 12th, 2003
"The group A streptococcal C5a peptidase (SCPA) is a major surface virulence protein that facilitates the establishment of local infection by group A streptococci (GAS). We measured the human immune response to SCPA, using a standardized indirect enzyme-linked immunosorbent assay," investigators in the United States report.
"Paired acute and convalescent serum samples from children with GAS-associated pharyngitis were assayed, and a strong immune response to SCPA was demonstrated that was independent of the infecting M type and the age of the patient," said Anita Shet and colleagues...
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Source: Vaccine Weekly (2003-11-12)
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