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Vaccine Development

Simultaneous measurement of pneumococcal polysaccharide antibodies reported

Published in Vaccine Weekly, November 12th, 2003

Researchers have developed a method for simultaneous measurement of antibodies to 23 pneumococcal capsular polysaccharides.

According to published research from the United States, "We describe a fluorescent covalent microsphere immunoassay (FCMIA) method for the simultaneous (multiplexed) measurement of immunoglobulin G (IgG) antibodies to 23 pneumococcal capsular polysaccharide (PnPS) serotypes present in the pneumococcal polysaccharide vaccine (PPV23) licensed by the Food and Drug Administration, i.e., PnPSs 1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19A, 19F, 20, 22F, 23F, and 33F."

"In addition, the assay incorporates an...

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