HIV/AIDS Vaccine

Microarray profiling of antibody responses against SHIV developed

Published in Vaccine Weekly, December 10th, 2003

Scientists have developed a method of microarray profiling of antibody responses against simian-human immunodeficiency virus (SHIV).

According to a study from the United States, "We developed antigen microarrays to profile the breadth, strength, and kinetics of epitope-specific antiviral antibody responses in vaccine trials with a simian-human immunodeficiency virus (SHIV) model for human immunodeficiency virus (HIV) infection. These arrays contained 430 distinct proteins and overlapping peptides spanning the SHIV proteome."

"In macaques vaccinated with three different DNA and/or recombinant modified vaccinia virus Ankara (rMVA) vaccines encoding...

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Source: Vaccine Weekly (2003-12-10)

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