Published in Vaccine Weekly, December 10th, 2003
"Genetic immunization strategies have largely focused on the use of 'naked' plasmid DNA or the gene gun. However, there remains a clear need to further improve the efficiency and/or cost of potential DNA vaccines. The theoretical basis of our research is to rationally design genetic immunization methodologies for nanoparticle-based delivery systems of plasmid DNA, perhaps in combination with already commercially available needle-free devices, such as the Biojector 2000," scientists in the United States...
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