Published in Vaccine Weekly, January 28th, 2004
According to recent research from England, "We have evaluated the potential of endospores of the Gram-positive bacterium Bacillus subtilis as an oral vaccine delivery system. The key features of the B. subtilis spore as a vaccine are, non-pathogenicity, advanced cloning tools, extreme robustness, long-term storage properties and its current use as a probiotic for both humans and animals."
"We have shown previously that the spore germinates in the small intestine of the mouse and have exploited this attribute for heterologous...
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