HIV/AIDS Vaccine
Monoclonal antibodies show promise for AIDS vaccines
Published in Vaccine Weekly, March 3rd, 2004
According to a study from the United States, "Human immunodeficiency virus type 1 (HIV-1) is phylogenetically classified into groups and clades (or subtypes). Human neutralizing monoclonal antibodies (nMAbs), originally isolated from individuals infected with HIV-1 group M-clade B, neutralized not only primary HIV-1 clade B isolates in vitro but also primary isolates of other group M clades (A, C, D, E, and F). This corrected the previously held notion that primary HIV-1 isolates are resistant to neutralizing antibodies."
"Here we show that anti-HIV-1 group M-clade B nMAbs potently neutralized...
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Source: Vaccine Weekly (2004-03-03)
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