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Giardiasis Vaccine

 Giardia intestinalis antigens stimulate a Th2 immune response

Published in Vaccine Weekly, March 24th, 2004

Giardia intestinalis antigens stimulate a Th2 immune response.

"Giardia, a flagellated protozoan that infects the upper small intestine of its vertebrate host, is the most common parasitic protist responsible for diarrhea worldwide. Molecules released by the parasite, particularly excretory and secretory antigens, seemed to be associated with pathogenesis as well as with the expression of Giardia virulence. In the present work, we examined the effect of oral administration of Giardia intestinalis excretory and secretory antigens on systemic and local antibody response as well as on mucosal injuries in BALB/c mice," researchers in France...

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