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Parainfluenza Vaccine

Parainfluenza type 3 vaccine safe and effective in children

Published in Vaccine Weekly, March 31st, 2004

Parainfluenza type 3 cold passage mutant 45 live attenuated vaccine was safe and effective in healthy children 6 to 18 months old.

"A phase 2 evaluation of live attenuated parainfluenza type 3 (PIV3) -cold passage mutant 45 (cp45) vaccine was conducted in 380 children 6 to 18 months old; 226 children (59%) were seronegative for PIV3. Of the 226 seronegative children, 114 received PIV3-cp45 vaccine, and 112 received placebo. No significant difference in the occurrence of adverse events (i.e., runny nose, cough, or temperature {{>=}}38 degrees C) was noted during the 14 days after vaccination," scientists in the United States and Australia report.

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