Smallpox

Recommendations issued on development of drugs for vaccine side effects

Published in Vaccine Weekly, March 31st, 2004

The U.S. Food and Drug Administration has issued draft guidance for the development of drugs to treat the side effects of vaccination against smallpox with vaccinia virus.

The need for drugs to treat the side effects of this vaccine became acute after the terrorist attacks on September 11, 2001. Routine vaccination for smallpox in the United States had ended in the 1970s, when the disease stopped occurring naturally, but the potential threat that variola virus would be used as a weapon of terrorism has raised the possibility that a large-scale vaccination could be necessary in an emergency. Because the use of this vaccine may cause complications in some individuals, the...

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Source: Vaccine Weekly (2004-03-31)

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