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Influenza Vaccine

Influenza A viruses obtained from Vero cells by reverse genetics

Published in Vaccine Weekly, April 7th, 2004

High-yielding influenza A viruses obtained from African green monkey kidney (Vero) cells by reverse genetics.

"Influenza A viruses are the cause of annual epidemics of human disease with occasional outbreaks of pandemic proportions. The zoonotic nature of the disease and the vast viral reservoirs in the aquatic birds of the world mean that influenza will not easily be eradicated and that vaccines will continue to be needed. Recent technological advances in reverse genetics methods and limitations of the conventional production of vaccines by using eggs have led to a push to develop cell-based strategies to produce influenza vaccine," scientists writing in the Journal...

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