Tobacco Use
Immunization attenuates psychoactive effects of nicotine
Published in Vaccine Weekly, April 7th, 2004
"Despite the enormous health risks, people continue to smoke and use tobacco primarily as a result of nicotine addiction. As part of our immunopharmacotherapy research, the effects of active and passive immunizations on acute nicotine-induced locomotor activity in rats were investigated. To this end, rats were immunized with either a NIC-KLH immunoconjugate vaccine designed to elicit an antinicotine immune response, or were administered an antinicotine monoclonal antibody, NIC9D9, prior to a series of nicotine challenges and testing sessions," scientists writing in the journal Bioorganic and Medicinal...
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Source: Vaccine Weekly (2004-04-07)
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