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Vaccine Weekly

Susan Hasty, Publisher

Table of Contents . . . April 21st, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Vaccine Weekly | Other Publications

Anthrax Vaccine - Needle-free skin patch vaccination method for anthrax developed

Tuberculosis Vaccine - Efficacy of tuberculosis DNA vaccine varies with method of DNA introduction

HIV/AIDS Vaccine - Assays with extended incubation phases needed to monitor HIV vaccine trials

Influenza - Fatal human influenza A subtype H5N1 disease re-emerges

Malaria Vaccine - Live sporozoite vaccine under chloroquine therapy protects against malaria

Vaccine Safety - DtaP vaccine causes hypersensitivity to aluminum in children

Allergy Medicine - Lactic acid bacteria and allergen induce immune response in allergy model

Anthrax Vaccine - Guardsman who refused anthrax vaccine discharged from Army

Autism Risk Factor - Issues surrounding the MMR vaccine and autism discussed

Avian Influenza - Vaccination of infected flocks could backfire without proper surveillance

Bacillus Calmette-Guerin - Immunogenicity of recombinant BCG vaccine strains investigated

Breast Cancer Therapy - Exemestane and aromatase inhibitors play role in breast cancer management

Business Update - Embrex opens biotech plant in Scotland County

Cancer Vaccine - Exosomes act as potent cell-free peptide-based vaccines

Cancer Vaccine - High efficiency of low-affinity epitopes in cancer therapy reported

Cancer Vaccine - Natural killer T-like cells induced by thymoma expressing alpha-fetoprotein

Cancer Vaccine - Peptide-based vaccines for cancer immunotherapy reviewed

DNA Vaccine - Bacteria-mediated DNA transfer in gene therapy and vaccination reviewed

DNA Vaccine - Methylated CpG-containing plasmid activates immune system

Dendritic Cell Vaccine - Activation of dendritic cells translates innate into adaptive immunity

Diabetes Link - Danish study finds no link between childhood vaccinations and diabetes

Finance - Biologics company raises financing for working capital

Finance - Medical supply distributor reports increase in net loss

HIV Prevention - FDA accepts IND for unique HIV vaccine

HIV/AIDS Prevention - AIDS virus is vulnerable in initial stage of infection

HIV/AIDS Vaccine - HIV-1 infection blocked via CCR5 and CXCR4 receptors

Heart Disease Risk Factor - Signs of cerebral amyloid angiopathy-related inflammation reported

Immunotherapy - Incomplete tolerance to the tumor-associated antigen MDM2 investigated

Influenza - New human influenza vaccine research and development project initiated

Influenza Vaccine - Universal influenza vaccination in children not yet justified

Liver Cancer - IL-12 administration suppressed metastatic liver tumor unsusceptible to CTL

Lung Cancer - ASCO accepts BLP25 liposomal vaccine phase IIB trial results for presentation

Malaria Vaccine - Adjuvant combination enhances protective effect of malaria vaccine

Melanoma - Proteasomal targeting improves presentation of melanoma tumor antigen

Microencapsulation - Anionic microparticles deliver antigens from Neisseria meningitidis

Mucosal Immunization -  Bordetella pertussis acts as adjuvant and inhibitor of immune responses

Mumps Epidemiology - Genetic diversity of mumps virus found in oral fluid specimens

Non-Hodgkin Lymphoma - Monkey virus may hold clue for development of common blood cancer

Parainfluenza Virus - Parainfluenza virus polymerase mutations provide varying attenuation

Periodontal Disease - Periodontitis vaccine decreases local prostaglandin E-2 levels

Pneumococcal Vaccine - Revaccination with pneumococcal vaccine is effective in older adults

Polio Vaccine - Circulating vaccine-derived polioviruses reviewed

Polio Vaccine - Potential strategies for eradication of polio outlined

Polio Vaccine - Role of routine polio immunization in post-certification era reviewed

SARS - Company receives STTR research grant from NIH for a virion solvent treatment

SARS - Experimental SARS vaccine shows promise in mice

SARS - Vaccine shows promise in mice

Schistosomiasis - DNA Vaccine protects against Schistosoma mansoni

Schistosomiasis - Peptide vaccine shows promise against schistosomiasis and fascioliasis

Smallpox - Successful smallpox vaccine trial announced

Streptococcus Vaccine - Group B streptococcal protein rib and cholera toxin protect against infection

Thymic Carcinoma - Outcome of multimodality therapy for thymic carcinoma described

Tongue Cancer - Tumor-associated proteins in oral tongue carcinoma identified

Tuberculosis - Low number of new anti-TB drugs under development, says information provider

Tuberculosis Vaccine - Oral BCG vaccine in lipids protects against pulmonary tuberculosis

Uterine Cancer - Sentinel lymph node procedure in uterine cancers reviewed

Vaccine Adjuvant - Costimulatory ligand is efficient adjuvant for antiviral T cell responses

Varicella Vaccine - Effectiveness of live varicella vaccines reviewed

Varicella Vaccine - Varicella skin test antigen best to monitor response to varicella vaccine

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