Breast Cancer Vaccine

NY-ESO-1 shows promise as antigen for breast cancer vaccine development

Published in Vaccine Weekly, May 12th, 2004

NY-ESO-1 shows promise as an antigen for vaccine development to treat breast cancer patients with a poor prognosis.

According to recent research published in the journal Cancer Research, "NY-ESO-1 is a cancer/testis antigen expressed in normal adult tissues solely in the testicular germ cells of normal adults and in various cancers. It induces specific humoral and cellular immunity in patients with NY-ESO-1-expressing cancer.

"The aim of this study was to determine the frequency of NY-ESO-1 mRNA and protein expression in malignant and benign breast tumors. NY-ESO-1 mRNA expression was detected by conventional reverse transcription-PCR and...

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Source: Vaccine Weekly (2004-05-12)

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