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Vaccine Weekly

Susan Hasty, Publisher

Table of Contents . . . June 9th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Vaccine Weekly | Other Publications

Cancer Vaccine - Immature dendritic cells in irradiated tumors induce antitumor immunity

Cervical Cancer - HPV vaccines and cervical cancer reviewed

DNA Vaccine - Plasmid DNA integrates into host genomic DNA after injection

Vaccine Delivery - Live genetically modified bacteria may act as drug delivery tools

West Nile Virus - Pathogenesis and therapeutic options for West Nile virus reviewed

AIDS/HIV Vaccine - HIV replication reduced in cells with zinc finger transcription factor

Anthrax Vaccine - Conjugate induces antibodies to capsule of B. anthracis

Autism - Report finds no evidence links autism to mercury in vaccines

Autoimmune Hepatitis - Murine model of type 2 autoimmune hepatitis developed

Breast Cancer - CTLs to breast tumor-associated protein lyse breast cancer cells

Breast Cancer - Marketing applications submitted for Femara, a post-tamoxifen treatment

Business Update - Indian and U.S. drug companies enter marketing, distribution alliance

Business Update - VaxGen may restate results to narrow loss

Cancer Vaccine - Dendritic cell vaccine shows promise for tumors expressing CEA

Cancer Vaccine - Protection against MUC1-expressing mouse tumors requires T cells

Cholera Vaccine - Efficacy of immunization of oral cholera vaccine in Vietnam reported

Collaborations - Juvaris collaborates with RNA-based gene-inhibition technology company

Contraception - Contraceptive vaccines based on mouse sperm protein PH20 assessed

Dengue Fever - Protective versus pathologic immunity toward dengue virus explained

Drug Discovery - New report evaluates drug leads

Encephalomyelitis - Protective encephalomyelitis DNA vaccine linked to IFN-beta induction

Finance - Biopharmaceutical company reports first quarter 2004 financial results

Gastric Cancer - Streptococcal-derived OK-432 effective for ascites from gastric cancer

Genetic Engineering - Cytokine gene therapy reverts melanoma growth in mice

Genomics and Genetics - NRAMPI and vitamin D receptor genes shed light on disease associations

HIV/AIDS - HIV vaccine trial initiated by U.S. Army based on Therapore technology

HIV/AIDS Research - Prolonged HIV-1 culture increases its sensitivity to soluble CD4 neutralization

Hepatitis B Vaccine - HLA and cytokine polymorphisms linked to hepatitis B vaccine responses

Hookworm -  Ancylostoma ceylanicum protein shows promise for hookworm vaccine

Infectious Disease Vaccine - Vaccines for infectious diseases with cutaneous symptoms reviewed

Influenza - APIC calls on healthcare facilities to improve flu-shot rates among workers

Influenza - New influenza immunization guidelines hailed by vaccine maker

Influenza - Study: Intranasal influenza vaccine shows higher efficacy rate

Influenza Vaccine - Influenza challenge of Th2/Tc2 response causes Th2/Tc1 response in lung

Influenza Virus - Influenza A virus PB1-F2 gene reported in recent Taiwanese isolates

Lactococcus - IL-12 produced and secreted in active form by Lactococcus lactis

Leishmaniasis - Gene encoding protective Leishmania amazonensis protein characterized

Leishmaniasis - L14 ribosomal protein from Leishmania braziliensis characterized

Malaria Vaccine - Humoral response against Plasmodium vivax protein retained for 30 years

Melanoma - TAP-1 technology corroborated in models of skin cancer

Meningitis -  Neisseria meningitidis lipoprotein required for virulence

Meningitis Vaccine - Polysaccharide-protein conjugates protect against N. meningitidis

Mumps - Analysis of mumps virus isolates during Swiss outbreak reported

Mumps - Study of mumps outbreak due to genotype H in Korea in 1999 reported

Mumps - Two new genotypes of mumps virus in Japan proposed

Mycobacterium Vaccine - Profiling of leprosy and tuberculosis patients aids vaccine development

Neisseria - PorA variable regions of Neisseria meningitidis characterized

Patents - Company receives broad patent for purified adenoviral compositions

Pediatric Vaccinations - Parents will push vaccine restrictions next year

Personnel - Paul Wehrle, researcher who helped eradicate smallpox, dead at 82

Pertussis Vaccine - Acellular pertussis vaccines possess increased safety in children

Plague - $1M contract signed to study vaccine against plague

Polio Vaccine - African nations step up polio battle as vaccine opponents signal end to boycott

Polio Vaccine - Polio model through mucosal infection in transgenic mice developed

Prostate Cancer - Dendritic cell vaccine for prostate cancer immunotherapy possible

Prostate Cancer - Salvage radiotherapy for treatment of prostate cancer reviewed

Prostate Cancer - Special protocol assessment granted from FDA for trial of GVAX vaccine

Prostate Cancer Therapy - Therapy for rising PSA after prostate cancer treatment reviewed

Receptor Studies - Protein-carbohydrate and protein-peptide interactions studied by NMR

Smallpox Vaccine - Smallpox vaccine adverse effects linked to cytokine level alterations

Theileriosis - Indirect ELISA for diagnosing tropical theileriosis developed

Tick-Borne Disease - Titration of Theileria parva tick-derived stabilates reported

Tuberculosis - Temporal expression profile of M. tuberculosis infection reported

Vaccinations - Oklahoma law encourages students to get meningitis vaccinations

Vaccine Research - New network will research fatal reactions to smallpox vaccine

Virology - Mechanisms and biomedical applications of virus entry reviewed

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