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Hookworm

 Ancylostoma ceylanicum protein shows promise for hookworm vaccine

Published in Vaccine Weekly, June 9th, 2004

Ancylostoma ceylanicum excretory-secretory protein 2, an immunoreactive protein produced by adult hookworms, shows promise as a target for vaccination.

According to recent research published in the journal Infection and Immunity, "Hookworms remain major agents of global morbidity, and vaccination against these blood-feeding parasites may be an attractive complement to conventional control methods. Here we describe the cloning of Ancylostoma ceylanicum excretory-secretory protein 2 (AceES-2), a novel immunoreactive protein produced by adult worms. Native AceES-2 was purified from excretory-secretory (ES) products by reverse-phase high-pressure liquid...

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