Hepatitis A Vaccine

Live and inactivated hepatitis A vaccines induced immunity in children

Published in Vaccine Weekly, August 4th, 2004

Live attenuated and inactivated hepatitis A vaccines induced anti-HAV immune responses in children.

"The immunogenicity of a live attenuated HAV vaccine and an inactivated HAV vaccine was compared. Altogether 117 children were vaccinated with either the inactivated or the live attenuated vaccine. Children were bled at months 1, 6, 7, 12, and 24, and the anti-HAV total IgG antibody and IgG subclass profile were assessed," researchers in China report.

"In both vaccinated groups, the geometric mean titer (GMT) of anti-HAV peaked 7 months after the initial dose and declined during the following months," said Xuan-Yi Wang and colleagues at Fudan...

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Source: Vaccine Weekly (2004-08-04)

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