Malaria Vaccine

RTS,S+TRAP malaria vaccine shows promise for infant immunization

Published in Vaccine Weekly, August 4th, 2004

An RTS,S+TRAP malaria vaccine, formulated in the AS02A adjuvant system, appears promising for immunization of infants.

According to a study from the United States, "Malaria vaccine RTS,S combined with thrombospondin-related anonymous protein (TRAP) and formulated with AS02A (RTS,S+TRAP/AS02A) is safe and immunogenic in adult humans and rhesus monkeys (Macaca mulatta). Here, RTS,S+TRAP/AS02A was administered on a 0-, 1-, and 3-month schedule to three cohorts of infant monkeys, along with adult comparators. Cohort I evaluated 1/5, 1/2, and full adult doses, with the first dose administration at one month of age; cohort 2 monkeys received full adult doses, with the...

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Source: Vaccine Weekly (2004-08-04)

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