AIDS/HIV Therapy
Protective T-cell epitope in p15gag of leukemia virus identified
Published in Vaccine Weekly, August 11th, 2004
"Recent studies have demonstrated an essential role of Gag-specific CD4+ T-cell responses for viral control in individuals infected with human immunodeficiency virus type 1. However, little is known about epitope specificities and functional roles of the Gag-specific helper T-cell responses in terms of vaccine-induced protection against a pathogenic retroviral challenge. We have previously demonstrated that immunization with Friend murine leukemia virus (F-MuLV) Gag proteins protects mice against the fatal Friend retrovirus (FV) infection," investigators in...
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Source: Vaccine Weekly (2004-08-11)
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