Pneumococcal Vaccine
Killed nonencapsulated cells protect mice against pneumococcal colonization
Published in Vaccine Weekly, September 1st, 2004
According to a study from the United States and Brazil, "Intranasal challenge of C57BL/6 mice with Streptococcus pneumoniae serotypes 6B, 14, and 23F produced colonization of the middle ear and NP. Intranasal vaccination with ethanol-killed nonencapsulated cells with adjuvant protected both sites."
"Of four nontoxic adjuvants tested, the cholera toxin B subunit was most effective and least nonspecifically protective," wrote Richard Malley and collaborators at Harvard University and the...
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Source: Vaccine Weekly (2004-09-01)
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