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Vaccine Weekly

Susan Hasty, Publisher

Table of Contents . . . September 8th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Vaccine Weekly | Other Publications

Brain Cancer Vaccine - Mesenchymal stem cells have antitumor effect in rat glioma model

Cancer Vaccine - Plasmid DNA in microparticles stimulates durable T cell responses

Haemophilus Vaccine - Synthetic polysaccharide vaccine against Haemophilus influenzae developed

Influenza Vaccine - Immunostimulant patch enhances immune responses to influenza virus vaccine

Malaria Vaccine -  Plasmodium antigen region elicits antibodies reactive with placental isolate

AIDS/HIV Vaccine - Candidate HIV type 1 vaccines elicit long-term memory B-cell responses

AIDS/HIV Vaccine - Codon optimization of HIV Tat enhance cell-mediated immune responses

AIDS/HIV Vaccine - Glycoprotein microarrays are useful tools in HIV glycobiology

AIDS/HIV Vaccine - HIV-1 Tat(1-72) protein-coated nanoparticles elicit strong immune responses

AIDS/HIV Vaccine - Hemagglutinating virus protein induces immune response with HIV vaccine

AIDS/HIV Vaccine - Heterologous envelope immunogens contribute to AIDS vaccine protection

AIDS/HIV Vaccine - Multi-subtype gp160 DNA immunization induces neutralizing anti-HIV antibodies

Acanthamoeba Vaccine - Novel mannose-binding protein of Acanthamoeba characterized

Allergy Medicine - Protein fused to Fc epsilon receptor enhances lymphocyte responses

Alzheimer Disease Vaccine - Anti-beta-amyloid antibodies generated via phage display technology

Anthrax - Dermatological aspects of anthrax reviewed

Avian Influenza - Contract awarded to develop vaccine against H9N2 avian influenza

Avian Influenza - New vaccine seeks to tame bird flu

Business & Finance - Biopharmaceutical company announces 32% revenue increase for second quarter 2004

Business and Finance - Pharmaceutical company reports second quarter, clinical development results

Cancer Vaccine - Binding patterns reveal tumor-specific epitope of epithelial mucin

Cancer Vaccine - Dendritic cell and fibroblast fusions possess antitumor effects

Cancer Vaccine - Dendritic cell vaccine induces tumoricidal CD8+ cytotoxic lymphocytes

Cancer Vaccine - Epigenetically altered tumor cell vaccine developed

Cancer Vaccine - Genetic adjuvants enhance efficacy of vaccine against Her-2/neu tumor antigen

Cancer Vaccine - IL-18-secreting fibroblasts prolong survival of tumor-bearing mice

Cancer Vaccine - Immunotherapy of cancer reviewed

Cancer Vaccine - Non-CpG motif oligonucleotides for cancer vaccination developed

Cancer Vaccine - Pemetrexed (ALIMTA) is novel multitargeted antineoplastic agent

Cancer Vaccine - T-cell responses in patients vaccinated with melanoma vaccine reported

Candida Vaccine - Antibody response to Candida albicans cell wall antigens reviewed

Cervical Cancer - New DNA vaccine targets proteins expressed in cervical cancer cells

Cholera Vaccine - Biosafety aspects of live oral Vibrio cholerae vaccine strain examined

Cholera Vaccine - Oral cholera vaccination can play role in controlling cholera outbreaks

Collaborations - Companies collaborate to provide needle safety for 2004 season flu vaccine

DNA Vaccine - Bacteriophage lambda is highly stable DNA vaccine delivery vehicle

Drug Delivery - Fear of needles could become a thing of the past.

Enterococcal Infection - Patent issued for Enterococcus antigens and vaccines

Epstein-Barr Virus - Epstein-Barr virus protein sufficient for transactivation of superantigen

Finance - Biotech products company reports second-quarter income of $12.1M

Finance - ISS-focused company reports $2.9 million second-quarter loss

Finance - Telomerase technology company reports Q2 loss of $8.9 million

Gastroenterology Vaccine - Activity of E. coli phages have implications for phage therapy

HIV/AIDS - Positive data reported for epitope-based HIV-1 vaccine

Helicobacter Vaccine - Plasmid encoding H. pylori urease induces specific antibody response

Helicobacter Vaccine - Regulatory T cells suppress H. pylori-reactive immunopathological T cells

Hepatitis B Vaccine - Hepatitis B surface S and preS2 antigens expressed in Solanum tuberosum

Hepatitis E Diagnosis - ELISA for hepatitis E detects antibodies to genotypes 1, 2, 3, and 4

Herpesvirus Vaccine - Virus expressing HSV-2 glycoproteins protects against HSV-2 challenge

Human Papillomavirus Vaccine - Dendritic cells and Langerhans cells both cross-prime T cells

Inflammation - Wood smoke increases expression of two mucin genes in rat airways

Influenza - U.S. Centers for Disease Control asks parents to start scheduling flu shots for children

Influenza Vaccine - Immune responses to intranasal influenza vaccine determined

Leishmaniasis Vaccine -  Quillaja saponaria sapogenins protect against visceral leishmaniasis

Lymphoma Vaccine - Novel diffuse large B-cell lymphoma cancer testis antigen identified

Malaria Vaccine - Small peptide induces complete protection against malaria

Malaria Vaccine - Splenic dendritic cell subsets prime and boost CD8 T cells

Meningococcal Vaccine -  N. meningitidis vesicles and lipo-oligosaccharide protect against septic shock

Meningococcal Vaccine - Meningococcal conjugate vaccine loses effectiveness after 1 year

Mergers & Acquisitions - Gene expression company announces acquisition of Digital Gene Technologies

Mergers & Acquisitions - Pharmaceutical company announces provisional results of offer to buy Aventis

Microencapsulation - Poly(lactic-co-glycolic acid)-based nanoparticulate system characterized

Microencapsulation - Subcutaneous immunization allows uptake of diphtheria vaccine

Moraxella Vaccine - Outer membrane proteins of Moraxella catarrhalis characterized

Mucosal Immunization - Salivary gland genetic vaccine improves systemic immune responses

Multiple Sclerosis - Potential therapeutic options for multiple sclerosis reviewed

Myelodysplastic Syndrome - Cytokine induces maturation of dendritic cells in myelodysplastic syndrome

Personnel - Cell-therapy company announces executive appointments

Personnel - Drug-discovery company names George Poste to board of directors

Personnel - Riaz Bandali joins board of electroporation company

Personnel - Therapeutic immunotherapy vaccine manufacturer announces new leadership

Plague Vaccine - Vaccine expressing Yersinia pestis antigen protects against plague

Pneumococcal Vaccine - Colony blot assay useful for detection of multiple pneumococcal serotypes

Poxvirus Vaccine - Understanding of poxvirus pathogenesis advanced by deleting viral genes

Respiratory Syncytial Virus - DNA delivery systems against respiratory syncytial virus infection compared

SARS Vaccine - Structural proteins of SARS coronavirus contribute to protective immunity

Smallpox Vaccine - Basics of smallpox reviewed

Smallpox Vaccine - Smallpox vaccine reactions and contraindications reviewed

Streptococcus Vaccine - Plasmid encoding pac gene of Streptococcus prevents dental caries

Streptococcus Vaccine - Vaccines of Streptococcus polysaccharides and T cell epitope developed

Tetanus - BLA submitted to FDA for Adacel vaccine

Tuberculosis Vaccine - Mycobacterial lipoarabinomannan and related lipoglycans reviewed

Tuberculosis Vaccine - New vaccines against tuberculosis entering human clinical trials

Vaccine Adjuvant - Adjuvant improves protection induced by vaccine against N. meningitidis

Vaccine Adjuvant - European union regulations for vaccine adjuvants and delivery systems listed

Vaccine Adjuvant - ISCOMATRIX adjuvant induces potent humoral and cellular immune responses

Vaccine Adjuvant - Immunobiology of Tomatine adjuvant reviewed

Vaccine Adjuvant - Poly-beta amino ester-containing microparticles enhance vaccine activity

Vaccine Adjuvant - Relations between lipopeptide adjuvants and Toll-like receptor explored

Vaccine Adjuvant - Vaccine adjuvants play vital role in vaccine efficacy

Vaccine Delivery - Drug delivery systems reviewed

Vaccine Delivery - Oral delivery system containing A/Panama influenza hemagglutinin optimized

Vaccine Delivery - Pluronic F127-based systemic vaccine delivery systems reviewed

Vaccine Delivery - Transcutaneously deliverable adjuvants modulate immune responses

Vaccine Development - New evidence on antigen presenting cells and antigens reviewed

Vaccine Efficacy - DNA vaccine potency in rhesus macaques enhanced by electroporation

Vaccine Efficacy - Efficacy of plasmid vaccines correlates with long-term antigen production

Vaccine Research - BioPort gets approval for new anthrax vaccine tests

Vaccine Research - Eligible plasma donors defined under new CDC program

Vaccine Research - Government collecting blood from soldiers to create anthrax vaccine

Vaccine Safety - Adjuvant hydrocarbon oil components of vaccines may induce autoimmunity

Vaccine Safety - Live viral vaccines safe in patients with partial DiGeorge syndrome

Vaccines - Colleges urge students to protect themselves against meningitis

Vaccines - Individual cancer, virus vaccines promote healthy future for biotechnology company

Vaccines - Students without shots sent home from school

Vaccines - Vaccines ruined when refrigerator goes awry

Vaccinia Vaccine - Vaccinia virus inhibition of PKR involves N-terminal domains of E3L

Vaccinia Virus - Sequence-independent acylation of vaccinia virus inclusion protein reported

Virology - Protective gene may enhance vaccine responses

Virology Vaccine - Lentiviral transduction of dendritic cells confers antiviral immunity

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