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Brain Cancer Vaccine
Mesenchymal stem cells have antitumor effect in rat glioma model
September 8th, 2004
Genetically engineered mesenchymal stem cells have an antitumor effect in a rat glioma model. "The prognosis of patients with malignant glioma is extremely poor, despite the extensive surgical treatment that they receive and recent improvements in adjuvant radio- and chemotherapy. In the present study, we propose the use of gene-modified mesenchymal stem cells (MSCs) as a new tool for gene therapy of malignant brain neoplasms. Primary MSCs isolated from Fischer 344 rats possessed excellent migratory ability and exerted inhibitory effects on the proliferation of 9L glioma cell in vitro," scientists in Japan report. "We also confirmed the migratory...
Source: Vaccine Weekly (2004-09-08)
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