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Haemophilus Vaccine
Synthetic polysaccharide vaccine against Haemophilus influenzae developed
September 8th, 2004
Researchers have developed a synthetic conjugate polysaccharide vaccine against Haemophilus influenzae type b. "Glycoconjugate vaccines provide effective prophylaxis against bacterial infections. To date, however, no commercial vaccine has been available in which the key carbohydrate antigens are produced synthetically. We describe the large-scale synthesis, pharmaceutical development, and clinical evaluation of a conjugate vaccine composed of a synthetic capsular polysaccharide antigen of Haemophilus influenzae type b (Hib)," investigators in Cuba report. "The vaccine was evaluated in clinical trials in Cuba and showed long-term...
Source: Vaccine Weekly (2004-09-08)
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