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Meningococcal Vaccine
N. meningitidis vesicles and lipo-oligosaccharide protect against septic shock
September 8th, 2004
Outer membrane vesicles (OMVs) and detoxified lipo-oligosaccharide (DLOS) obtained from Brazilian prevalent N. meningitidis serogroup B strains protect mice against homologous and heterologous meningococcal infection and septic shock. According to published research from Brazil and the United States, "Neisseria meningitidis (N. meningitidis) is a serious bacterial pathogen that causes life-threatening invasive bacterial infections especially in children below 2 years of age, teenagers and young adults. We have investigated the protective potential of outer membrane vesicles (OMVs) and detoxified lipo-oligosaccharide (dLOS) obtained from Brazilian...
Source: Vaccine Weekly (2004-09-08)
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