Malaria Vaccine
Plasmodium antigen region elicits antibodies reactive with placental isolate
Published in Vaccine Weekly, September 8th, 2004
According to a study from the United States and France, "The complications of malaria in pregnancy are caused by the massive sequestration of parasitized erythrocytes (PE) in the placenta. Placental isolates of Plasmodium falciparum are unusual in that they do not bind the primary microvasculature receptor CD36 but instead bind chondroitin sulfate A (CSA). Pregnant mothers develop antibodies that recognize placental variants worldwide, suggesting that a vaccine against malaria in...
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Source: Vaccine Weekly (2004-09-08)
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