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Moraxella Vaccine

Outer membrane proteins of Moraxella catarrhalis characterized

Published in Vaccine Weekly, September 8th, 2004

Researchers have characterized outer membrane proteins G1a and G1b of Moraxella catarrhalis.

According to recent research published in the journal Vaccine, "Moraxella catarrhalis is an important cause of otitis media, sinusitis, and lower respiratory tract infections in patients with chronic obstructive pulmonary disease. The purified outer membrane of M. catarrhalis contains a 29-kDa band, previously named outer membrane protein G1 (OMP G1). Polyclonal antiserum to the OMP G1 band was used to screen a genomic lambda phage library and the gene for OMP G1a was cloned and sequenced."

"Analysis of outer membrane by...

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