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AIDS/HIV Vaccine

SIVmac Gag p27 capsid protein gene expression in potato reported

Published in Vaccine Weekly, September 29th, 2004

Researchers have achieved SIVmac Gag p27 capsid protein gene expression in potatoes.

According to published research from the United States, "A cDNA encoding the simian immunodeficiency virus type (SIVmac ) Gag capsid protein was introduced into Solanum tuberosum cells by Agrobacterium tumefaciens-mediated transformation methods. The gag gene was detected in the genomic DNA of transformed leaf tissues by PCR DNA amplification. Immunoblot analysis of transformed potato plant extracts with anti-Gag monoclonal antibody showed that biologically active Gag protein was synthesized in transformed tuber tissues."

"Based on ELISA...

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