Bacteriology

Heat-shock proteins and host-pathogen interactions reviewed

Published in Vaccine Weekly, October 6th, 2004

Scientists review heat-shock proteins and the host-pathogen interaction during bacterial infection in a recent issue of Current Opinion in Immunology.

"Heat-shock proteins (HSPs) are expressed at high levels by bacterial pathogens during adaptation to intracellular survival. Both host and pathogen heat-shock proteins contribute to immunity by receptor-mediated activation of the innate immune response and by participation in the presentation of antigens for the adaptive immune response," investigators in England report.

"Manipulation of these interactions presents a potential route to improved control of infection by vaccination or...

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Source: Vaccine Weekly (2004-10-06)

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