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Vaccine Weekly

Susan Hasty, Publisher

Table of Contents . . . October 20th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Vaccine Weekly | Other Publications

AIDS/HIV Vaccine - Site mapping in HIV genome may provide new approach to vaccine design

Anthrax Vaccine - DNA vaccine protects mice against challenge anthrax STI spores

Hypertension Vaccine - Vaccine elicits anti-angiotensin I antibodies in hypertensive subjects

Microencapsulation - Microspheres induce adult-like CD8+ cytotoxic T cell responses

Prostate Cancer Vaccine - Antigen-derived peptides induce CTLs in prostate cancer patients

AIDS/HIV Vaccine - HLA class I serotypes important in vaccine efficacy assessments

AIDS/HIV Vaccine - Parenteral and mucosal DNA vaccination enhances SHIV infection control

Adenovirus Vaccine - Simian virus-tainted adenovirus vaccine does not increase cancer risk

Alzheimer Disease - Zinc-binding agonists affect recognition of beta-amyloid epitopes

Bioterrorism - Company gets contract for development of new vaccine adjuvants for biodefense

Cancer Therapy - Efficacy and safety for cancer immunotherapy preclinical results published

Cancer Vaccine - Antitumor responses promoted by bone marrow from immunized donors

Cancer Vaccine - Clinical trial initiated for novel therapeutic DNA cancer vaccine

Cancer Vaccine - Dendritic cell vaccine enhances IFN gene therapy for malignant glioma

Cancer Vaccine - Dendritic cells partially protect against intracerebral viral challenge

Cancer Vaccine - HSP70 expression in apoptotic cells correlates with antitumor efficacy

Cancer Vaccine - Heat shock protein tumor vaccine enhances immune responses

Cancer Vaccine - Poor immunogenicity of tumor antigen due to peptide-MHC-I instability

Cancer Vaccine - Tumor lysate-pulsed cells safe and effective for urological cancers

Cancer Vaccine Development - Killing malignant not normal B cells important for vaccine development

Childhood Immunizations - Researchers and policy makers asked to "fast track" access to childhood vaccines

Colon Cancer - Eloxatin to receive expanded indication in Europe for early-stage colon cancer

Contraception - Efficacy of anti-fertility vaccine compared in male animals

Cytomegalovirus Vaccine - Cytomegalovirus immune evasion proteins do not prevent T-cell response

DNA Vaccine - TLR9- and TLR9+ mice display similar immune responses to DNA vaccine

Dengue Virus Vaccine - Homotypic interaction domain of core protein of dengue virus identified

Diphtheria Vaccine - Diptheria toxin expressed in Streptococcus fails to neutralize toxicity

Encephalomyelitis - Amino acid copolymers amerliorate encephalomyelitis

Encephalomyelitis - T cells specific for onconeuronal antigen mediate encephalomyelitis

Grants - Federal grant will increase testing of newborns in U.S. heartland

HIV/AIDS Epidemiology - Act now to avoid a major HIV/AIDS epidemic in Western Pacific region, WHO says

HIV/AIDS Treatment - HIV vaccine trial moving to enroll last cohort of volunteers

Head and Neck Cancer - Immunological aspects of head and neck cancer reviewed

Hepatitis - Biotechnology company names clinical advisory board

Hepatitis B - WHO stresses importance of childhood immunization against hepatitis B

Hepatitis B Vaccine - Hepatitis B vaccination effective in intravenous drug users

Hepatitis B Vaccine - Practical difficulties in managing hepatitis B in Asia-Pacific reported

Herpesvirus Vaccine - Herpesvirus induces IFN-alpha via Toll-like receptor pathways

Human Papillomavirus Vaccine - DNA vaccine targeting HPV type 16 oncoprotein E6 developed

Human Papillomavirus Vaccine - Human papillomavirus in cervical cancers in Mozambique genotyped

Immunization - Montana chicken pox vaccination rate well below national average

Immunology - Trafficking of anti-complement receptor antibody investigated

Influenza - Association launches flu-shot locator

Influenza - Highmark flu immunization campaign reduces care costs by an estimated $6.4M

Influenza - Importance of influenza vaccination as season opens stressed by U.S. officials

Influenza - NIH grant awarded for development of cell culture-based influenza vaccine

Influenza - New Mexico says it is time to get your flu shot

Influenza - Newest recommendations highlight the urgency for childhood influenza vaccination

Influenza - Vaccines are first line of defense for flu prevention, antivirals can play role

Influenza Vaccination - Nurses' association opposes mandatory flu vaccination policy

Influenza Vaccine - Virus-immunoglobulin complexes involved in early virus elimination

Influenza Virus - Active NF-kappa B signaling is prerequisite for influenza infection

Leishmaniasis Vaccine - Current status of leishmaniasis vaccine development reviewed

Leishmaniasis Vaccine - Progress in vaccine research for visceral leishmaniasis reviewed

Leukemia Vaccine - Leukemia-derived dendritic cells become cells that stimulate T cells

Lung Cancer Vaccine - Peptides eliciting multiple responses in lung cancer identified

Lymphoma Vaccine - EBNA1-specific CD4+ T cells are key for control of Burkitt lymphoma

Malaria - Role of Plasmodium falciparum genes in malaria in pregnancy reviewed

Melanoma - Enrollment completed in phase III trial of Canvaxin

Melanoma - U.S. FDA authorizes start of phase 2 clinical trial on melanoma vaccine

Melanoma Vaccine - Immune responses to peptide epitope in melanoma patients described

Meningitis - Parents encouraged to schedule missed vaccine doses of Prevnar for children

Meningococcal Disease - FDA panel recommends licensure of Menactra vaccine

Microencapsulation - Encapsulated oral enterotoxigenic E. coli vaccine developed

Microencapsulation - pH-triggered microparticles for peptide vaccination developed

Monoclonal Antibodies - Monoclonal antibodies and therapeutics reviewed

Mucosal Immunization - Effect of particle size on transport across nasal mucosa studied

Mucosal Immunization - Improving M cell mediated transport across mucosal barriers reviewed

Patents - Companies win patents supporting Alzheimer disease immunotherapy treatments

Polio Vaccine - Simian virus-tainted polio vaccine does not raise childhood cancer risk

Prostate Cancer - Combination trial to study MDX-010 with GVAX prostate cancer vaccine

Prostate Cancer Vaccine - DNA vaccine elicits immune response in patients with prostate cancer

Prostate Cancer Vaccine - Gene-based therapy in prostate cancer reviewed

Rabies - More than 100 in Minnesota town require rabies shots

Respiratory Syncytial Virus - Recombinant respiratory syncytial viruses characterized

Respiratory Syncytial Virus - V beta 14+ T cells mediate disease induced by RSV G glycoprotein

Smallpox - FDA clinical hold for ACAM2000 removed, BLA submission planned

Streptococcus Vaccine - Group A Streptococcus strains causing epidemics analyzed

Tuberculosis - CDC funding to be used for development of TB vaccine trial sites in India

Tuberculosis Vaccine - DNA vaccine activates CD8+ cells and reduces lung injury in TB

Vaccine Adjuvant - Coding sequence optimization enhances enterotoxin expression in tobacco

Vaccine Development - Antigen injection into anterior chamber activates splenic CD8+ cells

Vaccine Efficacy - Effect of freezing rate and excipient on vaccine infectivity compared

Vaccine Efficacy - Pseudovirus encoding IL-2 restores immune responses to vaccines

Vaccine Vector - Modified vaccinia virus induces moderate activation of dendritic cells

Virology Vaccine - Progress on vaccine strategies against viral infections reported

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