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Meningitis Vaccine

PorA-specific differences found in antibody avidity after Men B vaccine

Published in Vaccine Weekly, November 3rd, 2004

Investigators found PorA-specific differences in antibody avidity after vaccination with a hexavalent Men B outer membrane vesicle vaccine in children.

According to recent research from the Netherlands, "A clinical phase II trial with an experimental hexavalent outer membrane vesicle (OMV) vaccine (HexaMen) containing six different porin A (PorAs) was carried out in toddlers (2 to 3 years) and schoolchildren (7 to 8 years) in the Netherlands. HexaMen exists of two OMVs each containing three different PorA types. The serum bactericidal activity (SBA) after vaccination against the six PorAs was significantly different and was higher in toddlers than in...

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