Mucosal Immunization

NALT- versus Peyer's-patch-mediated mucosal immunity reviewed

Published in Vaccine Weekly, November 10th, 2004

Researchers review NALT- versus Peyer's-patch-mediated mucosal immunity in a recent issue of Nature Reviews Immunology.

"Recent studies indicate that the mechanism of nasopharynx-associated lymphoid tissue (NALT) organogenesis is different from that of other lymphoid tissues. NALT has an important role in the induction of mucosal immune responses, including the generation of T helper 1 and T helper 2 cells, and IgA-committed B cells. Moreover, intranasal immunization can lead to the induction of antigen-specific protective immunity in both the mucosal and systemic immune compartments," scientists in Japan report.

"Therefore, a greater...

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Source: Vaccine Weekly (2004-11-10)

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