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Vaccine Weekly

Susan Hasty, Publisher

Table of Contents . . . November 24th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Vaccine Weekly | Other Publications

AIDS/HIV Vaccine - Parenteral vaccine adjuvants promote mucosal anti-HIV immune responses

Anthrax Vaccine - Anthrax proteins associated with germination and outgrowth identified

Cancer Vaccine - Heat shock protein gp96 elicits anti-tumor CD8 T cell cytotoxicity

Meningococcal Vaccine - Putative vaccine antigens from Neisseria meningitidis identified

Nicotine Vaccine - Riboflavin used for antibody-catalyzed oxidation of nicotine

AIDS/HIV Vaccine - DNA vaccine elicits efficient CD8+ T cell response to HIV epitope

AIDS/HIV Vaccine - HIV-1 protease cleavage site in human C1-inhibitor identified

AIDS/HIV Vaccine - Poxviruses expressing HIV protein stimulate cytotoxic T-cell responses

Adenovirus - Fiber protein encoded by late region of bovine adenovirus characterized

Allergy Medicine - Regulation of IL-1 beta and its inhibitor by epithelial cells described

Alzheimer Disease - Loci of susceptibility to amyloid precursor protein identified

Alzheimer Disease - New oral vaccine shows promise

Anthrax - U.S. to buy 75 million doses of vaccine

Anthrax Vaccine - Anthrax protective antigen predictive of serum anti-toxin activity

Anthrax Vaccine - Grant provides $3.5 million for anthrax vaccine study

Arthritis Therapy - Effects of iNOS inhibition on collagen-induced arthritis described

Asthma Therapy - Anti-IgE antibody omalizumab relieves airway inflammation in asthma

Bacteriology Vaccine - IgG2 recognizing phosphorylcholine protects against bacterial pathogens

Bovine Viral Diarrhea - Bovine viral diarrhea virus with deletions protects calves

Business & Finance - Biotechnology company receives $5 million financial commitment

Business Update - Biotech applies for ASE listing, updates status of infectious diseases research

Business Update - Company opens nucleic acid amplification testing laboratory

Cancer Therapy - Substance may improve cancer immune therapy, vaccines

Cancer Vaccine - Biotech receives patent allowance for nonlethal hemocyanin extraction method

Cancer Vaccine - Control parameters for dendritic cell-T cell interaction determined

Cancer Vaccine - OX40L exhibits anti-tumor therapeutic efficacy in murine tumor model

Cervical Cancer - Investigational vaccine reduces risk of HPV-related cervical cancer

Chickenpox Vaccine - Varicella screening in adolescents is cost-effective

Chlamydia Pneumoniae Vaccine - DNA vaccine plus booster protects against Chlamydia pneumoniae

Contraception - Heat shock protein acts as efficient carrier for GnRH vaccine

DNA Vaccine - Serine/threonine kinase modulates bacteria-induced IL-12 production

Dendritic Cell Vaccine - Poly(lactic-co-glycolic acid) enhances maturation of dendritic cells

Dengue Vaccine - Dengue infection enhanced by sera from dengue-vaccinated children

Diagnostics - Diagnostics company donates rapid HIV tests in China

Drug Delivery - Initial human clinical results of transdermal vaccination study 'promising'

Edwardsiella Vaccine - Membrane protein of Edwardsiella tarda is vaccine candidate

Finance - Chronimed reports positive Q1 results; merger with MIM on track

Finance - Medical products distributor announced financial results

Flu Vaccine - Arkansas flu shots almost gone

Flu Vaccine - Coconino, Arizona, officials to administer flu shots

Flu Vaccine - Flu shot lottery winners recieve their prize

Flu Vaccine - Hawaii to hold flu shot clinics for chronically ill

Flu Vaccine - Illinois Governor pressures FDA for flu shot plan

Flu Vaccine - Local agencies in Michigan play key role in distribution of flu vaccine

Flu Vaccine - Majority of physicians say flu vaccine shortage is crisis, e-survey shows

Flu Vaccine - Minnesota nursing homes report they have enough flu vaccine

Flu Vaccine - Mississippi health officials say 50K more flu vaccines available

Flu Vaccine - Veterans Health Administration cancels flu shot clinics

Gastroenterology Vaccine - Regions in fimbrial adhesin FaeG suggest donor strand mechanism

HIV/AIDS - Pediatric HIV/AIDS medical centers to be built in Africa

Haemophilus - PCR used to determine serotype of Haemophilus influenzae strains

Haemophilus Vaccine -  Haemophilus influenzae type b conjugate vaccines reviewed

Haemophilus Vaccine - Intranasal vaccine reduces colonization of Haemophilus influenzae

Healthcare Coverage - Companion HealthCare to cover FluMist nasal spray

Hepatitis - Hepatitis study information presented at conference

Hepatitis B Virus - EMEA issues positive opinion on hepatitis B vaccine containing Corixa's MPL

Hepatitis B Virus - Hepatitis B cases down 89% among children, adolescents

Heymann Nephritis - Chemically modified renal antigen produces Heymann nephritis

Human Papillomavirus Vaccine - ISCOMATRIX adjuvant is suitable for use in anticancer vaccines

Immunizations - Missed opportunities for adult immunization in primary care outlined

Immunizations - Study indicates vaccine protects against cervical cancer

Immunology - Cellular immune responses can develop in humoral non-responders to HBV vaccine

Immunology - Loss of CD154 impairs Th2 extrafollicular plasma cell response

Immunology - Subnormal immunity to measles in found in HIV+ mothers and infant cord blood

Influenza - Annual vaccination associated with decreased risk of death in elderly

Influenza - CDC chief: Flu season off to slow start

Influenza - Flu vaccine maker taking action to return to market as reliable supplier

Influenza - Strategies offered for flu vaccine rationing

Influenza Vaccine - Efficacy of influenza vaccination in healthy adults decreases with age

Influenza Vaccine - FluMist producer announces expanded delivery

Influenza Vaccine - Stability of influenza hemagglutinin in vaccine bulk material studied

Influenza Vaccine - Technology released for rapid production of influenza vaccines

Japanese Encephalitis - Sera against ChimeriVax-JE vaccine protects against encephalitis virus

Leprosy Therapy - Immunotherapy increases effectiveness of treatment for leprosy

Leukemia Therapy - Guidelines to define therapeutic strategies for leukemia described

Malaria - Malaria protein that binds to placental cells may serve as vaccine target

Malaria Genomics and Genetics - Genetic diversity of malaria merozoite protein gene determined

Malaria Vaccine - Malaria vaccine based on Plasmodium Duffy binding protein evaluated

Measles Vaccine - Economic analysis of mass measles vaccination in South Africa reported

Measles Vaccine - Measles-specific CD4 T cell memory decreases in vaccinated subjects

Measles Vaccine - Patients should receive measles vaccine after stem cell transplantation

Melanoma - M-Vax registered for commercial marketing, distribution in France

Meningococcal Vaccine -  Neisseria meningitidis vaccine safe and immunogenic in infants

Meningococcal Vaccine - Peptide mimotopes of N. meningitidis polysaccharide described

Non-Hodgkin Lymphoma - Antibodies with activity against non-Hodgkin lymphomas characterized

Oncogenesis - Adenoma to carcinoma hTR expression not linked to promoter methylation

Personnel - Biopharmaceutical company announces new member of board of directors

Personnel - Guenter Schirmer, MD, named medical director by drug developer

Pertussis Vaccine - Pertussis vaccines provide mucosal immunization of murine neonates

Plague Vaccine - Genome content of live plague vaccines defined using DNA microarray

Pneumonia -  Streptococcus, Haemophilus, and Moraxella characterized

Poliovirus Vaccine - Multiplex PCR method for identifying vaccine polioviruses developed

Poliovirus Vaccine - No link found between intussusception and oral poliovirus vaccination

Product Licensing - Nonexclusive HCV license granted to Roche

Prostate Cancer - Luteinizing-hormone-releasing-hormone causes prostatic atrophy

Pythiosis Therapy -  Pythium insidiosum antigens effective against vascular pythiosis

Salmonella Vaccine -  Salmonella flagellin induces systemic and mucosal immune responses

Shigellosis -  Shigella-associated diarrhea common in rural Egyptian children

Smallpox - Potential return of smallpox, world's readiness discussed in journal article

Smallpox - Significant progress reported on smallpox vaccine

Streptococcal Vaccine -  Streptococcus pneumoniae serotype distribution in Hong Kong determined

Streptococcus Epidemiology - Invasive Streptococcus pneumoniae serotypes are least commonly isolated

Tetanus Vaccine - HIV lowers antibodies elicited by tetanus and diphtheria vaccination

Tuberculosis -  Mycobacterium avium strains exhibit differential virulence

Tuberculosis - Oregon Health & Science University gets grant for TB research

Tuberculosis Vaccine - CD27-negative CD4 T cells produce IFN-gamma upon mycobacteria challenge

Tuberculosis Vaccine - Chronic pneumonia occurs despite immune response to BCG

Tuberculosis Vaccine - New M. tuberculosis antigens are promising vaccine candidates

Tuberculosis Vaccine - Successful TB vaccine may need to suppress interleukin-4 activity

Type 2 Diabetes - Data demonstrate the potential of arimoclomol for the treatment of diabetes

Vaccine Adjuvant - Aluminum adjuvants reviewed

Vaccine Adjuvant - Artificial peptide induces Th2 immune response to antigens

Vaccine Adjuvant - CD40 antibody as adjuvant induces enhanced T cell responses

Vaccine Adjuvant - Non-toxic Stx derivatives from E. coli possess adjuvant activity

Vaccine Adjuvant - Protollin is novel adjuvant for intranasal vaccines

Vaccine Adjuvant - Squalene adjuvant better than aluminum hydroxide in rabies vaccine

Vaccine Adjuvant - Squalene vaccine adjuvant is safe

Vaccine Delivery - Alginate hydrogels act as controlled release protein carriers

Vaccine Development - Antigens expressed in Salmonella vectors using SPI-2 promoter

Vaccine Development - License agreement reached for MedPulser DNA Delivery System in two applications

Vaccine Development - Neutralizing antibodies prevent use of human GM-CSF in macaques

Vaccine Economics - Potential conflicts of interest in vaccine economics research reviewed

Vaccine Efficacy - Data sources compared to identify veteran vaccinations

Vaccine Efficacy - IL-15 is superior to IL-2 in generating of long-lived memory T cells

Vaccine Efficacy - Vaccine efficacy estimated from household data observed over time

Vaccinia Virus - Src switches from microtubule- to actin-based vaccinia virus motility

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