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Tetanus Vaccine

HIV lowers antibodies elicited by tetanus and diphtheria vaccination

Published in Vaccine Weekly, November 24th, 2004

Levels of protective antibody levels elicited by tetanus and diphtheria vaccinations were lower in HIV-infected patients than in uninfected patients.

According to a study from Brazil, "Tetanus and diphtheria (Td) antibodies were studied in HIV-1-infected women during puerperium. HIV group (n=61) was compared with Control group (n=101). Twenty-one women from HIV and 13 from the control group who had antibody levels lower than 0.1 IU/mL received a booster with Td vaccine. Antibodies were assessed by double antigen ELISA."

"Mean tetanus and diphtheria antibody levels from HIV group were lower than those from the control group," said Tatiana C. S....

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