Immunology
Cellular immune responses can develop in humoral non-responders to HBV vaccine
Published in Vaccine Weekly, November 24th, 2004
According to a study from France, "about 10% of health care professionals vaccinated against hepatitis B virus (HBV) fail to develop protective antibodies."
"We tested the capacity of peripheral blood lymphocytes from 121 health care professionals, including 76 non-responders, to proliferate to 4 HBV vaccines, examined the proliferating cells' subset, production of interferon (IFN)-gamma, interleukin (IL)-4 and IL-10, and for 22 subjects, the cytokine production genotype. Specific proliferative responses to at least one HBV antigen were noted in 75% humoral...
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Source: Vaccine Weekly (2004-11-24)
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