Susan Hasty, Publisher
Table of Contents . . . December 1st, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Vaccine Weekly | Other Publications
Dengue Vaccine - Mutations in dengue virus vaccine candidate decreases virus replication
Prion Disease - Recent developments in prion immunotherapy reviewed
SARS Vaccine - Immunodominant sites on spike protein of SARS coronavirus identified
Smallpox Vaccine - Myopericarditis reported following smallpox vaccination
Vaccine Development - Prime-boost strategy developed using Salmonella enterica Typhi
AIDS/HIV Vaccine - AIDS protection dependent on persistence of vaccine virus
AIDS/HIV Vaccine - HIV-1 Tat protein modulates generation of cytotoxic T cell epitopes
AIDS/HIV Vaccine - HIV-1 Tat vaccine protects against SHIV89.6P replication in monkeys
AIDS/HIV Vaccine - Inflammatory stimuli increase neutrophil binding of HIV
AIDS/HIV Vaccine - Pseudoviruses encoding gag induces HIV gag-specific mucosal immunity
AIDS/HIV Vaccine - Retroviral vectors used to analyze SIV/HIV-specific T cell responses
AIDS/HIV Vaccine - nef-deleted SHIV protects against pathogenic virus infection
Alzheimer Disease - Beta-sheet breaker peptide prevents Alzheimer's memory impairments
Alzheimer Disease - Complications of Alzheimer vaccination in nonhuman primates modeled
Alzheimer Disease - Neuroscientists awarded $1.1 million grant to improve Alzheimer vaccine
Anthrax - Company gets $877.5 million U.S. government contract to supply anthrax vaccine
Anthrax Vaccine - Plasmid DNA vaccine protects against aerosolized anthrax spores
Anthrax Vaccine - Vaccine protects cheetah and black rhinoceros against anthrax
Autoimmune Disease - Virus-induced auto-antibody responses characterized
Breast Cancer - Investigators awarded grants from U.S. DoD Breast Cancer Research Program
Business & Finance - Immunotherapeutics company sees Q3 revenue increase
Business & Finance - Pharma company reports third quarter 2004 results
Cancer Vaccine - Antibodies redirect cytolytic capacity of cytotoxic T lymphocytes
Cancer Vaccine - Cancer vaccines must break immune tolerance to malignant cells
Cancer Vaccine - IL-6 regulates dendritic cell differentiation through STAT3 activation
Cancer Vaccine - Lipid-core-peptides increase adjuvant activity of T cell peptides
Cancer Vaccine - Melanoma vaccination results presented at conference
Cancer Vaccine - PHB1/PHB2 identified as blood-borne tumor antigens
Cancer Vaccine - Susceptibility of tumors to immunotherapy changes during maturation
Canine Distemper Virus - DNA vaccine protects against lethal canine distemper virus challenge
Cervical Cancer - HPV vaccine shown to "substantially" reduce cervical cancer
Clinical Update - Company details clinical development plan for CG53135 and CR002
Contraception - Studies in male monkeys demonstrate that immunocontraception could work
Diabetes - Research institute announces discovery on the virus' role in autoimmune disease
Diabetic Nephropathy - Data show FG-3019 improves kidney function in late-stage disease model
Diagnostics - Whole blood cytokine detection assay to quantitate T-cells developed
Diarrhea - Treatment of diarrhea and dysentery in Thailand described
Diphtheria-Tetanus Vaccine - Persistent itching nodules caused by diphtheria-tetanus toxoid vaccines
Dysentery Vaccine - Cultural context of dysentery has implications for vaccine introduction
Encephalitis Vaccine - Formaldehyde-inactivated Japanese encephalitis virus vaccine developed
Encephalomyelitis - Autoimmune encephalomyelitis cured by Trypanosoma cruzi infection
Epstein-Barr Virus - Epstein-Barr virus antigen elicits anti-dsDNA and anti-Sm antibodies
Escherichia Coli - Repeated boosting with E. coli bacterin needed for high antibody levels
Finance - Biophharmaceutical company reports cash position, net cash expenditures for Q3
Finance - Drug developer of upper respiratory therapies reports third quarter financials
Finance - Genetics-based company reports third quarter 2004 financial results
Finance - TNFerade maker reports increase in revenues, dip in losses during Q3
Genomics - Biotechnology company submits re-examiniation request for Benitec
HIV/AIDS - Infectech, Inc., reports validation of mycobacteria avium complex kit
HIV/AIDS - New information on TRIZIVIR presented at conference
HIV/AIDS - Pharma company files application with FDA for antiretroviral agent
HIV/AIDS - Phase II data for HIV drug presented at conference
HIV/AIDS - Phase IIa study show Reverset potentially reduces HIV viral load
HIV/AIDS - VScan HIV test kits are being shipped to Japan
HIV/AIDS Therapy - Indian firm withdraws its HIV drugs from World Health Organization list
Hepatitis - Trial results for spi-VECTM oral immunotherapeutic vaccine reported
Hepatitis B - Britain should adopt universal hepatitis B immunization, says doctor
Hepatitis B - European authorities give positive opinion for Fendrix vaccine
Hepatitis B - Outbreak of hepatitis B in drug users causes high mortality
Hepatitis B Virus - Phase II trial data announced on new HBV vaccine
Herpesvirus - Aggresome-like structures form in herpes virus type 2-infected cells
Herpesvirus - Tests for antibodies against bovine herpesvirus 1 evaluated
Herpesvirus Vaccine - In vivo function of gamma-herpesvirus virion glycoprotein described
Human Immunodeficiency Virus - Structure of anti-human immunodeficiency virus type 1 antibody 2F5 reported
Immunization - Comprehensive screening detects new epitopes in hepatitis C virus NS3 antigen
Immunizations - Financial challenges of immunization reviewed
Immunology - Marginal zone B cells deposit immune complexes onto dendritic cells
Immunology - Oral mucosal immunology reviewed
Infectious Disease - Research institute announces $12 million in NIH contracts for smallpox research
Infectious Disease - Study compares hepatitis B treatments
Influenza - 340,000 doses of influenza vaccine to be distributed in Pennsylvania
Influenza - CDC and states announce plan to distribute 10.3 million flu shots nationwide
Influenza - CDC to include FluMist in vaccines for children program
Influenza - Computerized orders increase administration of influenza, pneumococcal vaccines
Influenza - Flu preparedness must become public health priority
Influenza Vaccine - 15,000 people request a flu shot in Arizona county vaccine lottery
Influenza Vaccine - Additional doses of flu vaccine available for at-risk people in Louisiana
Influenza Vaccine - Alaskan health officials begin distributing more flu vaccine
Influenza Vaccine - Aventis gets federal contract to make flu vaccine year-round
Influenza Vaccine - Colorado getting another 66,000 flu shots
Influenza Vaccine - Connecticut receives unexpected batch of flu vaccine
Influenza Vaccine - Enrollment complete for intranasal influenza vaccine trial
Influenza Vaccine - Flathead County, Montana, plans one more clinic with surprise flu shots
Influenza Vaccine - Inactivated vaccines for pandemic influenza reviewed
Influenza Vaccine - Kansas to receive 75,360 doses of flu vaccine from CDC
Influenza Vaccine - More flu vaccine headed to Iowa
Influenza Vaccine - Nanoparticle and emulsified influenza antigen vaccines developed
Influenza Vaccine - New Hampshire's order of flu vaccine arrives
Influenza Vaccine - North Dakota getting more flu vaccine
Influenza Vaccine - One million high-risk Pennsylvanians still can't get flu shots
Influenza Vaccine - Pennsylvania to get 340,000 additional doses of flu vaccine
Influenza Vaccine - Study of avian influenza in birds and humans may help develop vaccines
Influenza Vaccine - U.S. CDC to ship New Mexico 38,515 additional flu vaccine doses
Influenza Vaccine - Vermont Health Department, health agencies offered more flu clinics
Influenza Vaccine - Virginia health officials to get 232,000 doses of flu vaccine
Influenza Vaccine - Yuma County, Arizona, distributes flu vaccine to elderly
Malaria Vaccine - Quantitative Plasmodium sporozoite neutralization assay developed
Marek Disease - Mutations in meq linked to Marek disease viruses of high virulence
Measles-Rubella Vaccine - Rapid onset optic neuritis after measles-rubella vaccination reported
Melanoma Vaccine - Vaccine induces cytotoxic T lymphocytes in human melanoma
Monoclonal Antibodies - Method for production of antibody-producing hybridomas developed
Mucosal Immunization - Adjuvants and delivery systems for mucosal vaccination reviewed
Mucosal Immunization - Mucosal immunology of vaccines against nasopharyngeal bacteria reviewed
Mycoplasma Vaccine - Mycoplasma agalactiae strain is candidate for attenuated vaccine
Newborn Health - Respiratory syncytial virus trial initiated
Parvovirus Vaccine - Immune responses to human parvovirus B19 vaccine reported
Personnel - Life sciences company names member to board of directors
Personnel - Molecular test producer announces president for its U.S. subsidiary
Poliovirus - Heat-resistant poliovirus mutants characterized
Poliovirus Vaccine - Surrogate method for predicting poliovirus vaccine efficacy developed
Poxvirus Vaccine - Nucleoside/nucleotide analogs show promise against poxvirus infections
Prostate Cancer - E.U. approves Taxotere (docetaxel) in prostate cancer
Prostate Cancer - Pharma companies awarded NIH grants for prostate cancer immunotherapies
Rabies Vaccine - Live vaccinia-rabies virus recombinants protect against rabies
Reovirus Vaccine - Protective IgA and IgG bind to epitopes in reovirus adhesin sigma 1
Research Awards - Molecular studies institute wins $4.8 million NIH contract for smallpox vaccine
Ricin Vaccine - Elimination of partially unfolded state improves vaccine stability
Rotavirus Vaccine - T-cell-mediated immune responses in rotavirus infections defined
Rubella - German measles elimination advancing, says public health group
SARS Vaccine - Researcher says SARS vaccine unlikely soon; drug companies show scant interest
Schistosomiasis Vaccine - Schistosoma antigen protects against S. mansoni infection
Schistosomiasis Vaccine - Antigen peptides from Schistosoma dehydrogenase used for vaccines
Shigellosis - IL-8 regulates neutrophil recruitment in model of Shigella colitis
Shigellosis Vaccine - Acceptability of shigellosis vaccine in Vietnam explored
Shigellosis Vaccine - Health belief model aids shigellosis vaccine use in Thailand
Smallpox Vaccine - Membrane proteins of virions protects against vaccinia virus
Tuberculosis - Licensing agreement signed to develop, market new antituberculosis compounds
Tuberculosis Prevention - New TB vaccine clears first hurdle
Tuberculosis Vaccine - Mammalian cell-entry proteins expressed during TB infection in humans
Tumor Vaccine - Therapeutic HER2/Neu DNA vaccine blocks the growth of murine tumors
Typhoid Vaccine - Vaccination against typhoid fever in travelers is not cost-effective
Vaccine Adjuvant - Adjuvant Quil A affects immune stimulatory capacity of liposomes
Vaccine Development - Applications of Clostridium and Bacillus proteins reviewed
Vaccine Development - CD8+ T-cell priming regulated by cytokines of innate immune system
Vaccine Development - Coadministered antigens may afford better protection against hepatitis B
Vaccine Development - Company says skin immunization may expand flu vaccine supply
Vaccine Development - DNA vaccine aids chronic hepatitis B carrier non-responders
Vaccine Development - Pharma company releases results from Boostrix clinical study
Vaccine Development - Vector-based enhancement of ICAM-1 augments anti-tumor activity in mice
Vaccine Efficacy - Game theory applied to vaccination strategies
Vaccine Safety - H2 O2 -induced death of thymocytes delayed by vaccine preservative
Varicella Vaccinations - Arizona health officials pushing plan for chickenpox vaccinations
Virology - Long-term immune memory cells do not develop during chronic viral infections
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