Rotavirus Vaccine

T-cell-mediated immune responses in rotavirus infections defined

Published in Vaccine Weekly, December 1st, 2004

Scientists have defined T-cell-mediated immune responses in rotavirus-infected juvenile rhesus macaques.

"The appearance of virus-specific CD4+ and/or CD8+ T lymphocytes in peripheral blood of captive juvenile rhesus macaques (Macaca mulatta) was observed following rotavirus infection. These cell-mediated immune responses were measured following experimental or natural infection after rotavirus was isolated from stool specimens of asymptomatic animals. The virus isolated was a new strain of simian rotavirus that we named TUCH (for Tulane University and Cincinnati Children's Hospital)," researchers in the United States report.

"Restimulation of...

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Source: Vaccine Weekly (2004-12-01)

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