Susan Hasty, Publisher
Table of Contents . . . December 8th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Vaccine Weekly | Other Publications
Immunization - Continuous antigenic stimulation is new immunization strategy
Malaria Vaccine - Immunogenicities of Plasmodium vivax protein fragments compared
Malaria Vaccine - Merozoite protein protects against lethal malaria parasite challenge
SARS Virus - Native form of recombinant SARS coronavirus spike glycoprotein characterized
Tuberculosis Vaccine - BCG can subvert monocyte differentiation into dendritic cells
AIDS/HIV Pathogenesis - CD4+ T cell depletion in HIV occurs predominantly in gastrointestinal tract
AIDS/HIV Vaccine - Novel and promiscuous CTL epitopes in conserved regions of Gag identified
AIDS/HIV Vaccine - Therapeutic HIV vaccines reviewed
AIDS/HIV Vaccine - Vaccine provides T-cell-mediated protection in monkeys after SIV challenge
Actinomycetoma Vaccine - IgM protects mice from actinomycetoma infection by Nocardia brasiliensis
Addiction Medicine - Cocaine pharmacology and pharmacotherapies for its abuse reviewed
Adverse Side Effects - Rare cutaneous reactions arise following hepatitis B vaccine immunization
Allergy Medicine - Parenteral immunization to beta-lactoglobulin modifies intestinal structure
Alzheimer Disease - Immune responses to A-beta vaccine are different in C57BL/6 and B6D2F1 mice
Alzheimer Disease - Inhibitors of A-beta oligomerization identified
Anthrax - Company completes first phase of ThraxVax design
Aspergillosis - CpG oligodeoxynucleotides modulate airway inflammation in aspergillosis model
Awards - Fluid diagnostics company receives award
Biological Therapy - Type-1 innate and acquired immunity play crucial roles in tumor immunotherapy
Breast Cancer - Phage display library from lymph nodes of breast cancer patients constructed
Business & Finance - Biopharma reports third quarter 2004 results, clinical achievements
Business Update - Molecular diagnostics company announces expansion of diagnostic pipeline
Business Update - New company to develop, produce patient-specific cancer vaccines
Cancer Immunoprevention - Fused cell vaccination and CpG oligodeoxynucleotides reject tumor recurrence
Cancer Therapy - Skin cancer study using MedPulser Electroporation Therapy system begins
Cancer Vaccine - Listeria-based cancer vaccines segregate immunogenicity from toxicity
Cancer Vaccine - Dendritic cells boost antitumor activity of adoptively transferred T cells
Cancer Vaccine - Expression of the cell surface mucin gene family in adenocarcinomas reported
Cancer Vaccine - IL-13 antagonist and Pseudomonas toxin fusion protein is anticancer
Cancer Vaccine - Tumor vaccine therapy reviewed
Cancer Vaccines - Interleukin-15 transfection plus CD8+ T cells cause colon cancer rejection
Cholera Vaccine - Vibrio cholerae amino acid sequence induces protective antibodies
Cognition - Immunization may have long-term effects on cognitive performance
Collaborations - Anti-cancer vaccine R&D agreement signed
Cryptococcus Vaccine - Immunoglobulin against Cryptococcus glucuronoxylomannan is protective
DNA Vaccine - DNA vaccines induce epitope-specific CTLs against histocompatibility antigens
Dengue Virus - Dengue viral infections reviewed
Diphtheria Vaccine - Respiratory epithelial cells internalize Corynebacterium diphtheriae
Disease Prevention - African leaders, health activists push for money to fight disease
Drug Development - Cervical cancer's image as a niche market hinders drug development
Encephalomyelitis - ICAM-1 upregulation in allergic encephalomyelitis depends on TNF-alpha
Finance - INTERCEPT maker reports Q3 revenue of $3.5 million
Finance - Immune-focused company announces Q3 net loss of $4M
Finance - Transdermal drug delivery technology company reports Q3 financial results
Finance - Vaccine company adopts shareholder rights plan
HIV Treatment - Monoclonal antibody among HIV therapies discussed at human virology meeting
HIV/AIDS Prevention - Russian government lacks will to combat spread of HIV/AIDS, experts say
HIV/AIDS Treatment - Canadian HIV partnership lends financial support to phase 2 clinical drug trials
HIV/AIDS Treatment - Data involving Combivir presented at recent meeting
HIV/AIDS Vaccine - Role of gastrointestinal T cells in HIV pathogenesis reviewed
Helicobacter Vaccine - Mechanisms of vaccine-induced protection against H. pylori reviewed
Hemorrhagic Fever - Signal peptide of arenavirus glycoprotein forms mature G1-G2 complex subunit
Hepatitis C Virus - Payment received from GlaxoSmithKline relating to HEV vaccine
Human Papillomavirus - Inflammatory responses in cervical neoplasia suppressed in HIV-positive women
Human Papillomavirus - Methods of identifying new antigenic epitopes of HPV 16 developed
Human Papillomavirus - Prevalence of HPV infection differs for men and women
Human Papillomavirus Vaccine - Dendritic cell-based vaccines effective against HPV-associated tumors
Immunization - Accelerated hepatitis B vaccine schedules protect prisoners better
Immunology - B subunit of E. coli enterotoxin induces apoptosis in CD8+ T cells
Immunology - B1b lymphocytes confer T cell-independent long-lasting immunity
Immunology - Chemokine receptor-mediated delivery induces protective immunity in vivo
Immunology - Heat shock protein suicide gene-based tumor vaccine provokes antitumor activity
Immunology - Intestinal epithelial antigen induces mucosal CD8 T cell tolerance
Immunology - LFA-1 on CD4+ T cells required for optimal antigen-dependent activation
Immunology - Nondepleting CD4 antibody induces immunological tolerance in baboons
Immunology - Role of IgG2b in mucosal tolerance induction investigated
Influenza - WHO says flu vaccine coming within year
Influenza Outbreak - Flu season starts in Oregon
Influenza Vaccine - Alabama nursing homes still waiting for flu shots
Influenza Vaccine - Chiron asks British regulators to inspect flu vaccine facility
Influenza Vaccine - HHS head Thompson announces contract to support egg supply for flu vaccines
Influenza Vaccine - Hawaii opens flu shot clinics for chronically ill
Influenza Vaccine - Ineffective vaccine given to about 300 in Arkansas, health official says
Influenza Vaccine - Senator says money for new flu vaccine research probably on the
Influenza Vaccine - Utah lifting flu shot restrictions
Influenza Vaccine - Vermont to hold 17 flu shot clinics
Leishmaniasis Vaccine - Leishmania major exogenous antigens protects against infection
Leishmaniasis Vaccine - Central memory T cells mediate long-term immunity to Leishmania major
Leishmaniasis Vaccine - T cells mediate immunity to Leishmania major in absence of parasites
Leukemia Vaccine - Leukemic cells have high B7-H1 and B7.1 expression and resist lysis
Listeria Vaccine - Listeria monocytogenes aro mutants show promise as vaccine candidates
Lung Cancer - Cancer vaccine helped patients in phase IIb trial survive 4.4 months longer
Lyme Disease - Borrelia burgdorferi changes antigens based on host immune response
MMR Vaccine - Differential immune responses to MMR vaccine in Israeli children documented
Malaria Vaccine - Plasmodium yoelii proteins enhance protection against malaria
Malaria Vaccine - Anatomy of Plasmodium falciparum MSP-1 epitope mapped
Malaria Vaccine - Antigenic drift in Plasmodium vivax protein confers antibody resistance
Measles Vaccine - Measles vaccination rate in developed world
Melanoma - Data updates from phase 2 trial for metastatic melanoma drug presented
Melanoma Vaccine - Quiescent phenotype of tumor-specific CD8+ T cells following immunization
Meningitis Vaccine - Protection against N. meningitidis found without bactericidal activity
Meningococcal Vaccine - Distribution of protein variants among meningococci aids vaccine design
Meningococcal Vaccine - Intranasal immunization with liposomes plus meningococcal proteins studied
Mergers & Acquisitions - Biotechnology company amends merger agreement with HIV-focused pharm firm
Mergers & Acquisitions - Biotechnology holding company signs agreement to acquire Portage Biomed
Mergers & Acquisitions - Company amends merger agreement with V.I. Technologies
Neuropathy - Immunization protocols for motor axonal neuropathy rabbit model compared
Oncogenesis - Aged mice develop protective antitumor immune responses with costimulation
Oncology - Combined chemotherapy and immunotherapy generates tumor rejection
Patents - Canada-based biotechnology company receives U.S. patent for vaccine production
Pediatrics - Pediatric nutrition company lists steps to keep families well during flu season
Personnel - Biopharmaceutical company names new chief executive officer
Personnel - Flu vaccine maker names Jack Goldstein interim COO, Anne Hill VP of HR
Personnel - Haig takes over from father as chairman of the board
Pneumococcal Vaccine - Streptococcus pneumoniae protects against fatal pneumococcal challenge
Pneumococcal Vaccine - Multiplex opsonophagocytosis assay useful to monitor pneumococcal vaccine
Pneumonia - Seniors in South Carolina urged to get pneumonia shots
Preventive Medicine - Despite setbacks, strong growth seen in $7 billion vaccine market
Renal Cancer - Dendritic cell-tumor fusion vaccines being developed for renal cell carcinoma
Renal-Cell Cancer - Allogeneic stem-cell transplantation for renal-cell cancer reviewed
Respiratory Syncytial Virus - Signaling via prostaglandin receptor protects against RSV
Salmonella Vaccine - Attenuated Salmonella mutants cause fatal infections in mice
Salmonella Vaccine - B7 costimulatory molecules play role in antibody responses to Salmonella
Salmonella Vaccine - Delta yej Salmonella mutants induce superior CD8+ T-cell responses
Salmonella Vaccine - Live Salmonella vaccine protects against Salmonella enteritidis
Schistosomiasis Vaccine - Vaccine protects against tetanus and schistosomiasis in mice
Staphylococcus - Sigma factor B required for virulence in Staphylococcus aureus
Streptococcus Vaccine - IgA important in protecting against Streptococcus pneumoniae
Tetanus - Case report of tetanus in immunized, healthy adult and no point of entry
Tuberculosis - Tuberculosis and HIV co-infection is a symbiotic relationship
Tuberculosis Vaccine - CD8 T cell activation protects against pulmonary tuberculosis
Tuberculosis Vaccine - Guidelines for latent tuberculosis testing and treatment released
Vaccine Adjuvant - Association of antigens to ISCOMATRIX adjuvant improves CTL responses
Vaccine Adjuvant - Cannabinoid is an adjuvant and in vivo chemoattractant for dendritic cells
Vaccine Adjuvant - Vaccines that facilitate antigen entry into dendritic cells reviewed
Vaccine Development - HER-2 Protein AutoVac starts phase II trial in breast cancer
Vaccine Development - Promoters are important elements in the design of DNA vaccines
Vaccine Development - U.S. HHS buys new anthrax vaccine for stockpile
Vaccine Development - Vaccinia vector with antigen-linked calreticulin elicits an antitumor response
Vaccine Development - Vectors expressing hepatitis C virus E1 proteins display antigenicity
Vaccine Safety - Childhood vaccine finance and safety issues reviewed
Vaccinia Virus - Vaccinia virus mutants fail to initiate morphogenesis
Vector Development - Porcine adenoviral vectors are effective vehicles for gene delivery
West Nile Virus - Netherlands Vaccine Institute signs agreement to produce West Nile vaccine
Wilms' Tumor Gene Vaccine - Wilms' tumor gene peptide vaccine causes cancer regression
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