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Vaccine Weekly

Susan Hasty, Publisher

Table of Contents . . . December 15th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Vaccine Weekly | Other Publications

AIDS/HIV Vaccine - Non-neutralizing anti-HIV-1 antibody becomes neutralizing antibody

AIDS/HIV Vaccine - Three vectors encoding SIV antigens protected against SIV CD4+ T-cell loss

Allergy Vaccine - Epitope modulation of Bet v 1 reduces IgE binding but retains protein folding

Autoimmune Disease - Therapeutic vaccination using CD4+CD25+ antigen-specific regulatory T cells

Cancer Vaccine - Unique antigens for therapeutic cancer vaccines reviewed

AIDS/HIV Vaccine - Antigenicity of HIV-1 p24 produced in high yields from plants was preserved

AIDS/HIV Vaccine - Correlation between IFN-gamma secretion and cytotoxicity in memory T cells

AIDS/HIV Vaccine - Depo-Provera before SIV challenge eliminates lentivirus-induced protection

AIDS/HIV Vaccine - Recall antigen activation induces prompt release of CCR5 ligands from PBMC

AIDS/HIV Vaccine - Seventeen SIV-derived CD8+ T cell Mamu-A*02-restricted epitopes identified

AIDS/HIV Vaccine - Tat protein elicits production of neutralizing antibodies

Addiction Medicine - Neuroscience research on addictions reviewed

Allergy Medicine - Genetically engineered allergens fight allergic disease progression

Allergy Medicine - New peanut immunotherapy inhibits allergic response in preclinical studies

Alzheimer Disease - Immunotherapy for Alzheimer disease reviewed

Alzheimer Disease - Kv3.4 potassium channel subunit up-regulated in early Alzheimer disease

Animal Testing - Methods to reduce numbers of animals in quality control testing presented

Anthrax - Drug demonstrates survival benefits when given after anthrax exposure

Anthrax - U.S. government to procure BioThrax for nation's stockpile

Asthma - Effect of BCG vaccination in asthmatic schoolchildren determined

Atherosclerosis - Role of antibodies to oxidized LDL in atherosclerosis development reviewed

Autoimmune Disease - Therapeutic vaccines in autoimmunity reviewed

Avian Influenza - Bird flu vaccine expected to be ready by 2007

Business & Finance - Vaccine company reports Q2 net loss of net loss of $650,131

Cancer Vaccine - Antibody response improved after antigen-pulsed dendritic cell vaccine

Cancer Vaccine - Manipulating dendritic cell biology provides active immunotherapy of cancer

Cancer Vaccine - Mono-epitopic peptide-based vaccine induces regression of liver tumor

Collaborations - Alliance to fight one of China's most pressing health problems: hepatitis B

Collaborations - Third pandemic influenza vaccine agreement signed

Contraceptive Vaccine - Fusing molecular adjuvant to hCG protein antigen enhances humoral immunity

Drug Delivery - Spray dried PLGA/amifostine nanoparticles for oral delivery developed

Encephalitis - Model of encephalitis using cynomolgus monkeys developed

Enterovirus Vaccine - Cell culture process for enterovirus vaccine development optimized

Equine Influenza Virus - Two co-circulating strains of equine influenza should be included in vaccines

Finance - Cancer-focused company announces direct equity issuance

Finance - Epitope-focused company reports Q3 revenues of $2.1 million

Finance - RNAi company reports reduced losses in Q3

Food Allergy - BCG vaccine modulates intestinal and systemic response to beta-lactoglobulin

Guillain-Barre Syndrome - Study documents decline in paralytic disorder linked to influenza vaccine

HIV/AIDS Treatment - U.S. HHS secretary Thompson applauds efforts to fight HIV/AIDS in Tanzania

Haemophilus Vaccine -  Haemophilus influenzae type b vaccination provides indirect protection

Haemophilus Vaccine - Stochastic model of vaccine trials for endemic infections developed

Haemophilus Vaccine - Transmission of Haemophilus influenzae type b modeled

Helicobacter Therapy - Evolving therapy for Helicobacter pylori infection reviewed

Herpesvirus - Herpes simplex virus infections reviewed

Human Papillomavirus Vaccine - HPV-like particles encapsidating IL-2 adjuvant enhanced immunogenicity

Immunology - Chimera of lutropin receptor and chorionic gonadotropin subunit developed

Immunology - Mucosal and systemic immunity to intestinal infection in aged mice studied

Infection - Peptidoglycan not associated with sensing of bacteria by toll-like receptor 2

Infectious Bursal Disease Virus - Particles formed by infectious bursal disease virus protein characterized

Infectious Disease - Immunology experts move forward on worldwide research database

Influenza - First case of flu detected in South Dakota

Influenza - Next flu pandemic could kill 7 million people, according to WHO expert

Influenza Vaccine - Federal officials investigate flu vaccine smuggling

Influenza Vaccine - Flu vaccine nearly as abundant as in 2003 in New Mexico

Influenza Vaccine - Hawaii gets more flu vaccine for at-risk patients

Influenza Vaccine - Health director now plans to order more doses of flu vaccine

Influenza Vaccine - Method to measure T cell immunity to influenza vaccination developed

Influenza Vaccine - Nevadans to be offered 93,000 flu vaccine doses

Influenza Vaccine - Structured model of influenza virus replication in MDCK cells created

Influenza Vaccine - TCR V beta repertoire directed against influenza CTL epitope reported

Influenza Vaccine - Tennessee's flu shot plan inoculates elderly in facilities first

Influenza Vaccine - U.S., Russian pharmaceuticals sign contract to produce flu vaccines in Russia

Influenza Vaccine - Vermont to hold more flu clinics

Information Technology - Grid software developer selected by IBM to power world community research grid

Lyme Disease Vaccine - OspA protein of Borrelia burgdorferi vaccination results in neuropathy

Malaria Vaccine - Membrane antigen and merozoite protein protect against P. chabaudi malaria

Measles Transmission - Airplane measles exposure offers lessons on disease contact response

Measles Vaccine - Impact of declining vaccination on subclinical measles infections reported

Medical Ethics - Ethics of preventive vaccination programs explored

Mucosal Immunization - Delivery to gut addressin by parenteral targeting elicits local IgA responses

Poxvirus - Poxvirus protein forms a complex with left-handed Z-DNA

Poxvirus - Vaccinia virus kinase induces p53 downregulation by Mdm2-dependent mechanism

Prion Disease - Humoral immune response to prion protein correlates with protection

Prions - Oligomerization of proteolytic products in prions shown

Prostate Cancer - Provenge data: Vaccine therapy for prostate cancer is shown to extend survival

Renal Cancer - CD8+ cytotoxic T lymphocytes recognize renal carcinoma antigens

Rubella Vaccine - Immunization law revisions affect incidence of congenital rubella in Japan

Smallpox Diagnosis - Rapid detection method for vaccinia virus developed

Spondylitis - T cell epitopes in HLA-B27 mice linked to spondyloarthropathy identified

Toxoplasmosis Vaccine - Vaccination protects B cell-deficient mice against Toxoplasma gondii

Vaccine Adjuvant - Gut dendritic cells mobilize and mature after oral cholera toxin vaccine

Vaccine Delivery - Topical permeation enhancers deliver microparticles to Langerhans' cells

Vaccine Development - Bacterial heat shock proteins enhance class II MHC antigen processing

Vaccine Development - Gene-gun DNA vaccination intensifies RSV-induced lung pathology in mice

Vaccine Development - IFN-gamma enables cross-presentation of protein antigen in Langerhans cells

Vaccine Development - Naked sequence-stabilized mRNA vaccine generates immunity to diverse antigens

Vaccine Development - Protein to antigen fusion heightens the efficacy of DNA cancer vaccine

Vaccine Safety - Safety concerns regarding combination vaccines described

Vaccinia Virus Vaccine - Neutralizing antibody activities to vaccinia virus proteins are synergistic

Varicella - Wyoming health officials concerned with chickenpox cases

Varicella-Zoster Virus - Varicella-zoster virus genome cloned as artificial chromosome in E. coli

Virology - Influenza vaccination is not associated with liver transplant rejection

Virology Vaccine - Rapid response of marginal zone B cells to viral particles reported

Yellow Fever Vaccine - Risk of fatal adverse events linked to 17DD yellow fever vaccine determined

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