Immunology
Mucosal and systemic immunity to intestinal infection in aged mice studied
Published in Vaccine Weekly, December 15th, 2004
According to a study from the United States, "Systemic immunity is progressively impaired in aging, predisposing to morbidity and mortality from neoplasia and infectious disease. However, the effect of aging on mucosal immunity is controversial. To assess intestinal immunity in aging, young and aged mice were orally exposed to reovirus or cholera toxin (CT) and specific antibody and reovirus-specific cytotoxic T-cell (CTL) responses were assessed."
"As previously reported, aged mice immunized orally with CT mounted diminished intestinal IgA...
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Source: Vaccine Weekly (2004-12-15)
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