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Helminth Vaccine

Chronic immune activation associated with helminthic infections reviewed

Published in Vaccine Weekly, January 5th, 2005

Researchers review the chronic immune activation associated with chronic helminthic and human immunodeficiency virus infections in a recent issue of Clinical Microbiology Reviews.

"Chronic immune activation is one of the hallmarks of human immunodeficiency virus (HIV) infection. It is present also, with very similar characteristics, in very large human populations infested with helminthic infections. We have tried to review the studies addressing the changes in the immune profiles and responses of hosts infected with either one of these two chronic infections. Not surprisingly, several of the immune derangements and impairments seen in HIV infection, and...

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