Anthrax Vaccine

Adsorbed anthrax vaccine characterized by two-dimensional gel electrophoresis

Published in Vaccine Weekly, January 12th, 2005

Researchers have characterized an adsorbed anthrax vaccine by two-dimensional gel electrophoresis.

According to recent research from England, "The current U.K. anthrax vaccine is an alum precipitate prepared from static culture filtrate of the avirulent, unencapsulated Sterne strain of Bacillus anthracis. Protective antigen (PA) is regarded as the major immunogen in the vaccine and production conditions are intended to maximize the PA content. However, the precise composition of the vaccine is unknown and there are concerns that the observed side effects of vaccination may be caused by residual enzymatically active toxin components."

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Source: Vaccine Weekly (2005-01-12)

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