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Vaccine Weekly

Susan Hasty, Publisher

Table of Contents . . . January 19th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Vaccine Weekly | Other Publications

Cancer Vaccine - Dendritic cells fused with human cancer cells described

MMR Vaccine - Delaying MMR immunization lowering vaccination coverage in Sweden

Measles Vaccine - Peptide-conjugate vaccine may provide protection against measles in infants

SARS Vaccine - Receptor-binding domain of SARS protein induces neutralizing antibodies

West Nile Virus - ChimeriVax-West Nile virus vaccine safe and effective in macaque model

Amoebic Liver Abscess - Collagen-binding proteins protect hamsters from amoebic liver abscess

Amoebic Vaccine - Distribution of Entamoeba histolytica antibody response reported

Anthrax - Fast-acting vaccine starts working in mice within hours

Avian Influenza - Philosophy of fighting disease within European Union outlined

Bacteriology - Differentiated CACO-2 cells modulate cytokine release

Bacteriology - Norepinephrine increases adherence of E. coli to mucosa of colon

Bovine Viral Diarrhea Virus - Novel inactivated BVDV vaccine protects fetuses against BVDV infection

Brain Cancer Vaccine - Human leukocyte antigen-A24-restricted antitumor cell generated

Breast Cancer - CD8+ T cells from breast cancer patients recognize mammaglobin epitopes

Breast Cancer - Matrix metalloproteinases are prognostic in patients with breast cancer

Business Update - German company spins off new enterprise with peptide vaccine portfolio

Business Update - Pharma company acquires intellectual property right in immunotherapy

Cancer Therapy - Photocrosslinkable chitosan useful for endoscopic cancer therapy

Cancer Vaccine - Dendritic cells in vaccination therapies of human malignant disease reviewed

Cancer Vaccine - Methods to improve rituximab efficacy reviewed

Cancer Vaccine - Phase I study for antitumor CEA-TRICOM published

Cancer Vaccine - Tumor antigens and implications for cancer diagnosis and treatment reviewed

Candidiasis - Significance of Candida serology based on cell wall antigens reviewed

Chickenpox Vaccine - Effects of varicella vaccination on herpes zoster incidence studied

Childhood Immunization - Vaccine contributions to health highlighted at expert meeting

Colon Cancer - Chemotherapy useful for liver metastases from colorectal cancer

Dendritic Cells - Immortalized dendritic cell line with cross-priming ability developed

Equine Cutaneous Papillomatosis - Equine papillomavirus virus-like particles characterized

Finance - Biopharmaceutical company files shelf registration statement

Finance - Hawaii-based biopharma company awarded $15.5 million in NIH funding

Flavivirus Vaccine - Transmembrane domains of yellow fever virus proteins are localization signals

Foot-and-Mouth Disease - Small interfering RNA inhibit foot-and-mouth disease virus replication

Gastroenterology - Quantitative changes in gastric mucosal glycoproteins investigated

Global Health - Vaccine program makes strides in increasing immunization coverage

HIV/AIDS Screening - Company completes trials for two HIV rapid tests; nears PMA submission

HIV/AIDS Therapy - Invirase receives FDA marketing approval

Hepatocellular Carcinoma - Dendritic cells elicit T-cell-mediated immune responses to HCA587 protein

Human T-cell Lymphotropic Virus - Leukocyte T-cell peptide construct protects against vaccinia virus challenge

Immunization - Children of migrant mothers less likely to receive all immunizations

Immunology - TCR peptide-specific Tregs provide homeostatic control of immunity

Immunology - Timing of lipopolysaccharide injection affects immune responses

Inflammatory Bowel Disease - Autoantibodies in inflammatory bowel disease impairs antibiotic activity

Inflammatory Bowel Disease - Dendritic cell subpopulations in inflammatory bowel disease characterized

Inflammatory Bowel Disease - Expression of chemokine receptor CXCR3 in IBD mucosa described

Influenza - Three new flu cases reported in New Mexico

Influenza Vaccine - Changes in hemagglutinins and neuraminidases of influenza B viruses outlined

Influenza Vaccine - Intranasal virosome influenza vaccine induces strong immunity in ferrets

Influenza Vaccine - Parenteral influenza vaccine influences T cell-mediated immunity in adults

Influenza Vaccines - Flu vaccine available to larger Mississippi group

Influenza Vaccines - Indian Health Services gives New Mexico 10,000 flu vaccines

Influenza Vaccines - Poll reveals flu shot data

Influenza Vaccines - Restrictions on flu vaccine eased in South Carolina

Influenza Vaccines - Wisconsin lifts flu shot restrictions

Johne Disease Vaccine - Immune response to Mycobacterium avium paratuberculosis described

Leishmaniasis - Cutaneous and mucosal Leishmania strains isolated from same patient analyzed

Leishmaniasis - Insect galectins play role in parasite survival

Leishmaniasis - Pharmaceutical company receives approval to market leishmaniasis drug in Germany

Leishmaniasis Vaccine - Analog of human beta-casein fragment effective against Leishmania

Leukemia - Encouraging data reported from phase II trial of leukemia vaccine

Malaria Vaccine -  Plasmodium vivax merozoite surface protein 8 characterized

Malaria Vaccine - Method developed to produce antibodies specific for MSP-3 protein in mice

Medical Reporting - Year in medicine report from Harvard Medical School focuses on medical advances

Melanoma - Clearance granted to commence trials of autologous cell vaccine

Meningitis - Law requires colleges to provide meningitis information

Meningitis Outbreak - Enteroviruses responsible for outbreak of aseptic meningitis identified

Mucosal Immunization - Mucosal immune system reviewed

Pancreatic Cancer - Dendritic cell vaccine has antitumor effect against pancreatic cancer

Patent - Drug development company issued patent for regulation of mismatch repair

Personnel - Michael T. Sember named as president and CEO

Pharmaceutical Research - Antibody pharmacokinetics and pharmacodynamics reviewed

Pneumonia - Discovery of key protein's shape may lead to better bacterial pneumonia vaccine

Respiratory Syncytial Virus - Anti-G protein antibodies to RSV linked to G protein binding inhibition

Respiratory Syncytial Virus - Shifting immunodominance pattern of epitopes in RSV glycoprotein reported

Rotavirus Vaccine - Mutation of rotavirus genome alters expression of IRF3-interacting protein

SARS Vaccine - Fusion core of SARS-coronavirus spike protein characterized

Smallpox Vaccine - Cowpox virus host range gene affects vaccinia viral translation in HeLa cells

Smallpox Vaccine - Modified vaccinia virus vaccine protects against lethal challenge

Smallpox Vaccine - Potential of variola infection of macaques as smallpox model investigated

Smallpox Vaccine - Protein and genome analysis company awarded grant to develop smallpox vaccine

Stem Cell Research - Fetal, cord blood, and adult lymphocyte progenitors generate similar B cells

Tetanus Vaccine - Tetanus vaccination with IL-2 during HAART induces sustained T-cell responses

Toxoplasmosis - Rhoptries from Toxoplasma gondii tachyzoites isolated

Urinary Tract Infections - Company develops transmucosal vaccine for urinary tract infections in women

Vaccine Adjuvant - Resiquimod is new vaccine adjuvant for Th1 immune responses

Vaccine Development - Biopharma company submits marketing authorization for StaphVAX

Vaccine Development - Dendritic cell recruitment may broaden the value of DNA vaccines

Vaccine Development - T-cell receptor tetramers bind MHC-peptide complexes with high affinity

Vaccine Research - Company to launch cancer-vaccine research sub: BN ImmunoTherapeutics

Vaccine Vector - Adenoviral vector vaccine process to overcome anergy to antigens described

Varicella Vaccine - Effective varicella vaccine developed

Virology - Angiotensin-converting enzyme 2 is a SARS coronavirus receptor

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